Changes of pleural pressure after thoracic surgery

Journal of Thoracic Disease
Jin San BokSehoon Choi

Abstract

The negative pressure of the pleural cavity is critical to maintain lung expansion. However, the actual values of pleural pressure according to the phase of respiration after various types of pulmonary resection have not been well reported. The aim of this study was to measure the pleural pressure directly and to compare the results according to the extent of pulmonary resection. We manufactured a high-resolution digital manometer with which pleural pressure can be measured directly. A total of 43 patients who underwent thoracic surgery (lobectomy in 23, minimal resections in 20) were enrolled. The maximum, minimum, and mean pleural pressure was recorded during normal quiet breathing, forced breathing, and coughing, separately. During normal quiet breathing, the average values of pleural pressure at end inspiration, end expiration, and the mean pleural pressure were -17.7, -7.0 and -11.2 cmH2O in lobectomy group, and -14.3, -4.6, -8.3 cmH2O in the minimal/no-resection group, respectively. The mean pleural pressure was significantly lower in lobectomy group compared to the minimal/no-resection group (P=0.026). During forced respiration, the same values were -44.0, -4.2 and -18.9 cmH2O in the lobectomy group, and -29.8, -0.1 and ...Continue Reading

Citations

Mar 30, 2021·Advanced Drug Delivery Reviews·Matthew A BorrelliSteven R Little

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.