Changes of the growth plate in children: 3-dimensional magnetic resonance imaging analysis

Korean journal of pediatrics
Hyung Ho YunJi-Young Seo

Abstract

This pilot study assessed changes in the growth plate and growth rates in children during a 6-month period. The study included 31 healthy children (17 boys, 14 girls) under evaluation for growth retardation. Height, weight, bone age, insulin like growth factor-1 (IGF-1), and insulin like growth factor binding protein 3 (IGF-BP3) were measured at baseline and after 6 months. In addition, the diameter, thickness, and volume of the femoral and tibial growth plates were measured using magnetic resonance imaging. The mean bone age in boys and girls was 11.7 and 10.7 years, respectively. In boys, height (z score) (-0.2 vs. 0.0), weight (z score) (0.8 vs. 1.1), body mass index (BMI) (z score) (1.27 vs. 1.5), IGF-1 (ng/mL) (343.6 vs. 501.8), and IGF-BP3 (ng/mL) (5,088.5 vs. 5,620.0) were significantly higher after 6 months. In girls, height (z score) (-1.0 vs. -0.7), weight (z score) (-0.5 vs. 0.1), BMI (z score) (-0.02 vs. 0.3), IGF-1 (ng/mL) (329.3 vs. 524.6), and IGF-BP3 (ng/mL) (4,644.4 vs. 5,593.6) were also significantly higher after 6 months. In both sexes, the mean diameter and volume of the femoral and tibial growth plates were significantly increased 6 months later. No significant correlation was found between changes in the ...Continue Reading

References

May 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·G J BreurN J Wilsman
Jul 1, 1989·The Journal of Physiology·E B Hunziker, R K Schenk
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·A Mas, L Arola
Jul 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·N J WilsmanM K Clayton
Nov 5, 1998·Journal of Gerontological Nursing·K C Buckwalter
Mar 22, 2002·AJR. American Journal of Roentgenology·Kirsten Ecklund, Diego Jaramillo
Dec 13, 2003·Endocrine Reviews·B C J van der EerdenJ M Wit
Oct 6, 2005·Hormone Research·Ola NilssonJeffrey Baron
Jun 23, 2009·Journal of Biomechanics·Isabelle Villemure, Ian A F Stokes
Aug 3, 2011·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·AeRang KimBrigitte C Widemann

❮ Previous
Next ❯

Citations

Oct 16, 2019·Pediatric Radiology·Tal Laor, Diego Jaramillo
Feb 11, 2020·Journal of Magnetic Resonance Imaging : JMRI·Phuong DuongDiego Jaramillo
Oct 3, 2019·Magnetic Resonance Imaging Clinics of North America·Héloïse LerissonNathalie Boutry
Jan 5, 2022·Current Opinion in Pediatrics·María TucaMatías Sepúlveda

❮ Previous
Next ❯

Software Mentioned

Argus

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.