Changing geographical distribution of diabetes mellitus type 1 incidence in Austrian children 1989--2005.

European Journal of Epidemiology
Waldhoer ThomasAustrian Diabetes Incidence Study Group

Abstract

We investigated whether the significant spatial West/East trend of incidence of Diabetes mellitus Type 1 in Austrian children changed between 1989 and 2005. Additionally we tested, whether population density and mean body mass index of newborns is associated with incidence. All newly diagnosed cases aged 0-14 years in Austria (n = 2644), prospectively registered from 1989 to 2005 were allocated to 99 districts. Ecological regression and analysis was done by Bayesian hierarchical models including spatially correlated risks. In Austria, the incidence rose from 9.1/100.000 in 1989--1994 to 14.9/100.000 in 2001--2005. The spatial trend in the period 1989--1995, showing high incidence in the Eastern parts of Austria, disappeared. In the period 2001--2005 a significant inverse negative association of population density with incidence was found. Mean body mass index of newborns in the Austrian population is significantly positively associated with incidence. The observation of higher incidence in rural areas in Austria during recent years may reflect a lower exposure to protective environmental factors, e.g. infections early in life. The observed association with the BMI in newborns indicates that neonatal or prenatal metabolic aspect...Continue Reading

References

Mar 1, 1996·American Journal of Epidemiology·S RichardsonV Lasserre
May 20, 1999·European Journal of Pediatrics·B RamiE Schober
Dec 29, 2000·Diabetologia·T WaldhörUNKNOWN Austrian Diabetes Incidence Study Group
Apr 17, 2001·BMJ : British Medical Journal·L C SteneUNKNOWN Norwegian childhood Diabetes Study Group
May 29, 2002·Diabetologia·E A M Gale
May 3, 2003·Journal of Clinical Epidemiology·Edith SchoberUNKNOWN Austrian Diabetes Incidence Study Group
May 21, 2003·European Journal of Pediatrics·Thomas WaldhörUNKNOWN Austrian Diabetes Incidence Study Group
Apr 15, 2004·Journal of Epidemiology and Community Health·U Samuelsson, O Löfman
Feb 16, 2005·Intensive Care Medicine·F LemaireUNKNOWN ESICM Task Force on Legislation Affecting Clinical Research in the Critically Ill Patient
Apr 25, 2007·European Journal of Pediatrics·Edith SchoberUNKNOWN Austrian Diabetes Incidence Study Group

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Citations

Mar 21, 2012·Annual Review of Public Health·Amy H AuchinclossAna V Diez Roux
Oct 23, 2010·European Journal of Epidemiology·Vincent W V JaddoeAlbert Hofman
Jul 25, 2012·Journal of Attention Disorders·Adela Masana MarínInti Ney
Jan 31, 2020·Diabetic Medicine : a Journal of the British Diabetic Association·K Castillo-ReinadoJ Rosenbauer
Jul 3, 2008·Current Opinion in Endocrinology, Diabetes, and Obesity

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