Changing trends in end-stage renal disease due to diabetes in the United kingdom

Journal of Renal Care
C J Hill, D G Fogarty

Abstract

In some countries, diabetic kidney disease (DKD) is responsible for half of all new patients requiring renal replacement therapy (RRT). Understanding the relationship between early and later stages of DKD is important as it is a preventable cause of renal failure. This review aims to establish the trends in end-stage renal disease (ESRD) due to diabetes in the United Kingdom as the first step in this understanding. Using annual reports from the UK Renal Registry, we summarise the presentation, incidence, prevalence and survival of ESRD patients with diabetes over the last 10-15 years. Between 1995 and 2009, initiation of RRT in diabetes patients increased from 12.3 to 27.6 patients per million population (pmp). These rates are approximately five times less than those of Caucasians in the United States suggesting fundamental differences in early DKD management. Survival of diabetic patients on dialysis has improved such that prevalent numbers on RRT increased from 47 to 117 pmp in a 12-year period. A longer time to prepare patients for RRT is strongly related with better outcomes. In 2002, 23% of all patients with diabetic nephropathy were referred late, within 90 days of RRT start; by 2009, this figure had fallen to 11.2%. Acce...Continue Reading

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Citations

Jan 10, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Cécile Couchoud, Emmanuel Villar
Feb 6, 2014·Diabetologia·Frank G A AssogbaUNKNOWN French Renal Epidemiology and Information Network Registry
Sep 16, 2015·Journal of Clinical Medicine·Nicolas Roberto RoblesRoman Hernandez Gallego
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May 16, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Friedrich C PrischlUNKNOWN Austrian Dialysis and Transplant Registry
Oct 28, 2014·Nephrology·Christoph ThalhammerMarc Husmann
Sep 20, 2016·Journal of Internal Medicine·N J Brunskill
Apr 21, 2020·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Fang HuLiao Sun
Aug 21, 2014·Postgraduate Medicine·Ahmed H AbdelhafizJose M F de Oliveira
Dec 31, 2019·Journal of Diabetes Research·Dana PrídavkováMarián Mokáň

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