Changing Urban-Rural Disparities in the Utilization of Direct-Acting Antiviral Agents for Hepatitis C in U.S. Medicare Patients, 2014-2017.

American Journal of Preventive Medicine
Ping DuJeah Jung

Abstract

The advent of direct-acting antiviral agents for treating hepatitis C virus infection has made hepatitis C virus elimination possible. Rural patients with hepatitis C virus infection may be less likely to access direct-acting antiviral agents, but the real-world evidence is scarce on urban-rural disparities in direct-acting antiviral agent utilization. This retrospective cohort study was conducted in 2019-2020 using Medicare data to examine urban-rural disparities in direct-acting antiviral agent utilization among newly diagnosed patients with hepatitis C virus infection in 2014-2016. Direct-acting antiviral agent use was defined as filling ≥1 prescription for direct-acting antiviral agents during 2014-2017, and patient's urban-rural status was classified on the basis of their ZIP code of residence. This study evaluated the associations between multilevel factors and direct-acting antiviral agent use with a focus on urban-rural disparities. It also assessed changes over time in urban-rural disparities in direct-acting antiviral agent utilization using multivariable cause-specific Cox regression analyses with time-varying hazard ratios. Among 204,018 new patients with hepatitis C virus infection, about 30% received direct-acting...Continue Reading

References

Aug 1, 2000·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·S C StearnsH M Edin
Jun 14, 2002·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Timothy D McBride, Keith J Mueller
Jun 6, 2009·American Journal of Epidemiology·Bryan LauStephen J Gange
Jul 8, 2010·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Sanjeev AroraWesley Pak
Jun 3, 2011·The New England Journal of Medicine·Sanjeev AroraClifford Qualls
Feb 22, 2012·Annals of Internal Medicine·Kathleen N LyScott D Holmberg
Aug 13, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anil G SuryaprasadScott D Holmberg
Nov 26, 2014·Journal of Primary Care & Community Health·Ryan P WestergaardJames M Vergeront
Mar 11, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Viktor V ChirikovCharles D Howell
Jun 26, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·UNKNOWN AASLD/IDSA HCV Guidance Panel
Apr 12, 2016·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Vincent Lo ReJay R Kostman
May 11, 2016·JAMA : the Journal of the American Medical Association·Channa R JayasekeraAijaz Ahmed
Apr 19, 2017·Current Opinion in Virology·Roberta D'AmbrosioAlessio Aghemo
Apr 21, 2017·American Journal of Public Health·Fabienne Laraque, Jay K Varma
Jun 8, 2017·Journal of Clinical Gastroenterology·Philip R SpradlingUNKNOWN Chronic Hepatitis Cohort Study (CHeCS) Investigators
Jul 1, 2017·Quality Management in Health Care·Emily E DunnT Joseph Mattingly
Nov 21, 2017·The Lancet Infectious Diseases·Harel Dahari, Basmattee Boodram
May 26, 2018·Current HIV/AIDS Reports·Asher J SchranzWilliam C Miller
Jul 10, 2018·Clinical Therapeutics·Shashi N Kapadia, Kristen M Marks
Nov 7, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Megan G HofmeisterA Blythe Ryerson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

The Lancet. Gastroenterology & Hepatology
Nassim KamarQiuwei Pan
Revista española de quimioterapia : publicación oficial de la Sociedad Española de Quimioterapia
Ainhoa Fernández-YunqueraRafael Bañares
© 2021 Meta ULC. All rights reserved