PMID: 15244724Jul 13, 2004Paper

Chaotic flow and efficient mixing in a microchannel with a polymer solution

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Teodor BurgheleaV Steinberg

Abstract

Microscopic flows are almost universally linear, laminar, and stationary because the Reynolds number, Re, is usually very small. That impedes mixing in microfluidic devices, which sometimes limits their performance. Here, we show that truly chaotic flow can be generated in a smooth microchannel of a uniform width at arbitrarily low Re, if a small amount of flexible polymers is added to the working liquid. The chaotic flow regime is characterized by randomly fluctuating three-dimensional velocity field and significant growth of the flow resistance. Although the size of the polymer molecules extended in the flow may become comparable to the microchannel width, the flow behavior is fully compatible with that in a macroscopic channel in the regime of elastic turbulence. The chaotic flow leads to quite efficient mixing, which is almost diffusion independent. For macromolecules, mixing time in this microscopic flow can be three to four orders of magnitude shorter than due to molecular diffusion.

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Citations

Oct 31, 2013·Physics of Fluids·Yves DubiefJulio Soria
Sep 24, 2015·Biomicrofluidics·Shelly GulatiDorian Liepmann
Jan 20, 2018·Physical Review. E·Emmanuel L C Vi M PlanDario Vincenzi
Sep 9, 2017·Nature Communications·Eldad Afik, Victor Steinberg
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Oct 15, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Shelly GulatiSusan J Muller
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Jul 15, 2016·Physical Review. E·Alexandre de Chaumont Quitry, Nicholas T Ouellette
Feb 10, 2019·Micromachines·Jiayan Tai, Yee Cheong Lam
Jun 22, 2016·Soft Matter·Firoozeh BabayekhorasaniJacinta C Conrad
Aug 7, 2007·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Jia OuJonathan P Rothstein
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Dec 21, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Yonggun Jun, Victor Steinberg
Jun 15, 2006·Analytical Chemistry·Petra S DittrichAndreas Manz
Nov 6, 2021·Science Advances·Christopher A Browne, Sujit S Datta

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