Characterisation of cutaneous leishmaniasis in Matara district, southern Sri Lanka: evidence for case clustering

Pathogens and Global Health
K K G D U L KariyawasamN D Karunaweera

Abstract

Leishmaniasis is a neglected tropical disease transmitted by Phlebotomus spp. sand flies. Cutaneous leishmaniasis (CL) in Sri Lanka is caused by Leishmania donovani. Transmission patterns are different in Southern and Northern Sri Lanka. Current study examined the prevalence, risk factors and distribution of CL in Matara District, Southern Sri Lanka. Total of 2260 individuals from four District Secretariat divisions (DSDs) were screened by house to house surveys using an interviewer administered questionnaire. The study population had an age range of 1-90 years (median  =  43  ±  17.31), low monthly income ( < 20 000 LKR, 52.8%) and a male to female ratio of 1 : 2. Thirty eight patients were diagnosed by light microscopy, culture and/or PCR with a disease prevalence of 1.68%. Spatial mapping provided evidence for significant case clustering, which tended to be more prominent with proximity to forest areas. The risk factors identified were un-plastered brick walls, absence or low usage of protective measures against insect bites, low income and excessive time (>4 hours/day) spent outdoors. However, exposure of limbs while outdoors, unawareness about the disease, type of occupation, common water source as the mode of water supply...Continue Reading

References

Jun 11, 2003·The Ceylon Medical Journal·H V Y D SiriwardenaN D Karunaweera
Jul 1, 2004·Comparative Immunology, Microbiology and Infectious Diseases·P Desjeux
Jul 21, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·N D KarunaweeraJ P Dedet
Jan 18, 2006·Revista Da Sociedade Brasileira De Medicina Tropical·Elizabeth Castro MorenoMariângela Carneiro
May 15, 2007·Transactions of the Royal Society of Tropical Medicine and Hygiene·U S RajapaksaN D Karunaweera
May 23, 2007·International Journal for Parasitology·Paul A Bates
Jun 26, 2007·The Ceylon Medical Journal·P H AbeygunasekaraM de S Wijesundera
Oct 30, 2008·PLoS Neglected Tropical Diseases·Caryn BernJorge Alvar
Dec 20, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Sujeevi S K NawaratnaKosala Rajapaksha
Oct 7, 2009·The Journal of Parasitology·A C RosypalJ P Dubey
May 29, 2010·Annals of Tropical Medicine and Parasitology·H V Y D SiriwardanaN D Karunaweera
Jun 11, 2010·International Journal of Dermatology·Deepani RathnayakeRajiv De Silva
Mar 8, 2011·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Yusuf OzbelYoshitsugu Matsumoto
Jun 14, 2012·PloS One·Jorge AlvarUNKNOWN WHO Leishmaniasis Control Team
Dec 26, 2012·Pathogens and Global Health·Shalindra RanasingheFrancine Pratlong
Aug 7, 2013·The American Journal of Tropical Medicine and Hygiene·Shalindra RanasingheRenu Wickremasinghe
Jan 21, 2014·Tropical Medicine & International Health : TM & IH·Rohana SandanayakaSuneth Agampodi
May 17, 2014·Clinical Epidemiology·Paul D Ready
May 27, 2014·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·S N SemageS B Agampodi
Feb 27, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·D Gomez-BarrosoA Benito
Jul 18, 2015·Pathogens and Global Health·H V Y D SiriwardanaN D Karunaweera

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Citations

Aug 19, 2017·Pathogens and Global Health·H V Y D SiriwardanaN D Karunaweera
Mar 8, 2018·BMC Infectious Diseases·Devika IddawelaLanka Wijekoon
Jul 17, 2019·BMC Infectious Diseases·Bhagya DeepachandiYamuna Siriwardana
Feb 14, 2020·Acta Parasitologica·Anjalie Amarasinghe, Susiji Wickramasinghe
May 22, 2019·BioMed Research International·Yamuna SiriwardanaNadira D Karunaweera
Apr 30, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Andréa Flávia Luckwü de Santana GonçalvesCelivane Cavalcanti Barbosa
Jul 3, 2019·Journal of Tropical Medicine·Yamuna SiriwardanaNadira D Karunaweera
Dec 20, 2019·Emerging Infectious Diseases·Nadira D KarunaweeraGuofa Zhou
Apr 24, 2021·PLoS Neglected Tropical Diseases·Nadira D KarunaweeraGuofa Zhou
Jul 25, 2021·The Science of the Total Environment·Nerida Nadia H ValeroMaría Uriarte

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