Characterisation of the first complete genome sequence of the roe deer (Capreolus capreolus) papillomavirus

Virus Research
K ErdélyiKrisztina Ursu

Abstract

The complete genomic DNA of a novel roe deer (Capreolus capreolus) papillomavirus (CcPV1) was amplified and sequenced from fibropapillomatous skin lesions of a Hungarian roe deer. Viral DNA was detected by a pair of degenerate primers and the remaining genomic sequence was amplified by a long-template high-fidelity PCR and sequenced. The CcPV1 genome was 8032 bp long and contained open reading frames (ORFs) typical for Delta-papillomaviruses (E6, E7, E1, E2, E4, E5, E9, L2, and L1) and a 799 bp long untranslated regulatory region (URR). Phylogenetic analysis based on the 3861 bp long concatenated sequence of the E1-E2-L2-L1 ORFs and on separate alignments of all major ORFs using both neighbour-joining and maximum parsimony methods placed CcPV1 on a distinct branch between Ovine papillomavirus 1 and the other deer papillomaviruses within the Delta-papillomavirus genus, although pairwise nucleotide alignments of L1 ORF sequences determined highest identities with European Elk Papillomavirus (71.2%) and Reindeer Papillomavirus (70.3%).

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Citations

Nov 6, 2015·Journal of Wildlife Diseases·Federica SaviniAlessandra Scagliarini
Mar 7, 2009·Veterinary Microbiology·Károly ErdélyiNorbert Solymosi
Apr 8, 2011·The Journal of General Virology·A E UreO Forslund
Jul 9, 2009·Acta Veterinaria Hungarica·Károly ErdélyiTheodora Steineck
Nov 27, 2010·Veterinary Microbiology·Christian E LangeClaude Favrot
Aug 27, 2010·Trends in Microbiology·Ignacio G BravoMarc Gottschling
Mar 9, 2010·Virology·Hans-Ulrich BernardEthel-Michele de Villiers
May 29, 2013·Virology·Annabel Rector, Marc Van Ranst
May 20, 2020·Frontiers in Veterinary Science·Laura GallinaAlessandra Scagliarini
Apr 18, 2020·Frontiers in Veterinary Science·Samoa Zürcher-GiovanniniFrancesco C Origgi

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