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Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension

bioRxiv

Jan 20, 2020

Gi Fay MokAndrea Munsterberg

Abstract

The development of multicellular organisms is exquisitely regulated through differential gene activity, which governs cell differentiation programs. However, many details of spatiotemporal control of gene regulation are still poorly understood. We used the accessibility of chick embryos...read more

Mentioned in this Paper

Mesoderm Formation
Paraxial Mesoderm Formation
Genes, Homeobox
Cst8 protein, rat
Somite Development
Cartilage
Gene Rearrangement
Trunk Structure
Transcriptome
Vertebrates
6
Paper Details
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Characterising open chromatin identifies novel cis-regulatory elements important for paraxial mesoderm formation and axis extension

bioRxiv

Jan 20, 2020

Gi Fay MokAndrea Munsterberg

DOI: 10.1101/2020.01.20.912337

Abstract

The development of multicellular organisms is exquisitely regulated through differential gene activity, which governs cell differentiation programs. However, many details of spatiotemporal control of gene regulation are still poorly understood. We used the accessibility of chick embryos...read more

Mentioned in this Paper

Mesoderm Formation
Paraxial Mesoderm Formation
Genes, Homeobox
Cst8 protein, rat
Somite Development
Cartilage
Gene Rearrangement
Trunk Structure
Transcriptome
Vertebrates
6

Similar Papers Found In These Feeds

Chromatin Regulators: Differentiation

Chromatin regulators affect gene expression by influencing the access of proteins such as transcription factors to DNA. Here is the latest research on the role of chromatin regulating proteins on cellular differentiation.

Hox Gene Family

The homeobox genes (Hox gene family) encode for homeodomain-containing transcription factors, which are important in the regulation of embryonic development and cell differentiation. They have a conserved DNA binding domain that are found in the family of hox genes. Discover the latest research on hox gene family here.

Related Papers

Mechanisms of Development

Hoxa-5 acts in segmented somites to regulate cervical vertebral morphology

Mechanisms of DevelopmentMarch 7, 2013
Jessica W ChenJennifer H Mansfield
Paper Details
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