PMID: 8440419Feb 1, 1993Paper

Characteristic features of alcoholic liver disease in Japan: a review

Gastroenterologia Japonica
A TakadaM Tsutsumi

Abstract

The characteristics of alcoholic liver disease (ALD) in Japanese patients were reviewed and compared with those in Western countries. From the study in Japanese cases, it became clear that alcoholic fibrosis and chronic hepatitis induced by alcohol were types of ALD other than the traditional 3 types. Liver injury in Japanese cases was clearly milder than that in American cases. In American cases, the injury may be fully developed, because of greater alcohol and fat intake. This may be one reason why the two above types of ALD have not been mentioned in the literature of Western countries. In Japanese patients, hepatitis C virus (HCV) infection is not related to alcoholic fibrosis and alcoholic hepatitis. On the other hand, the prevalence of HCV markers was high in chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC) patients. Alcoholic hepatitis and chronic hepatitis are the high risk groups for the development of cirrhosis and the chronic hepatitis group is at high risk for the development of HCC. Although the risk is low in alcoholic fibrosis, some patients also develop cirrhosis. About half of the cases of cirrhosis may develop from alcoholic hepatitis and alcoholic fibrosis, and the remaining half cases may deve...Continue Reading

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Citations

Feb 1, 1996·Journal of Gastroenterology and Hepatology·W Cooksley
Sep 1, 1995·Journal of Gastroenterology and Hepatology·A Takada, M Tsutsumi
Mar 18, 2009·World Journal of Gastroenterology : WJG·Duygu Dee Harrison-Findik
Jul 22, 1999·Revista Do Instituto De Medicina Tropical De São Paulo·L C de OliveiraS R Valente
Dec 14, 2005·Alcoholism, Clinical and Experimental Research·Yutaka KohgoJunji Kato
Oct 1, 1995·Alcoholism, Clinical and Experimental Research·A YokoyamaM Hayashida
Apr 11, 2008·Journal of Gastroenterology and Hepatology·Yutaka KohgoJunji Kato
Mar 5, 2011·Journal of Clinical Biochemistry and Nutrition·Masayoshi YamadaTomiyasu Arisawa
Mar 3, 2007·Alcoholism, Clinical and Experimental Research·Takaaki OhtakeYutaka Kohgo
Sep 4, 2021·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Shogo TanakaShoji Kubo

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