Characteristic of chronic plaque psoriasis patients treated with biologics in Italy during the COVID-19 Pandemic: Risk analysis from the PSO-BIO-COVID observational study.

Expert Opinion on Biological Therapy
Marina TalamontiKetty Peris

Abstract

Background: The susceptibility of patients with chronic plaque psoriasis and the risks or benefits related to the use of biological therapies for COVID-19 are unknown. Few data about prevalence, clinical course and outcomes of COVID-19 among psoriatic patients were reported. The aims of this study were 1) to assess the prevalence and severity of COVID-19 in psoriatic patients treated with biologic agents during the first phase of the emergency (22 February to 22 April 2020) in Italy, and 2) to report the clinical outcomes of patients who have been exposed to individuals with confirmed SARS-CoV-2 infection. Methods: Patients with moderate-to-severe chronic plaque psoriasis, aged ≥18 years and undergoing treatment with biologic agents as of 22 February 2020, were eligible to be included in PSO-BIO-COVID study. Demographic and clinical characteristics of patients using any biologic for psoriasis treatment between 22 February and 22 April 2020 were registered. Results: A total of 12,807 psoriatic patients were included in the PSO-BIO-COVID study. In this cohort 26 patients (0.2%) had a swab confirmation of SARS-CoV-2 infection. Eleven patients required hospitalization and two died. Conclusion: The incidence of COVID-19 observed in ...Continue Reading

References

Mar 23, 2020·Journal of the American Academy of Dermatology·Mark LebwohlDedee F Murrell
Apr 7, 2020·The Journal of Dermatological Treatment·Federico BardazziAmbra Di Altobrando
Apr 7, 2020·JAMA : the Journal of the American Medical Association·Giacomo GrasselliUNKNOWN COVID-19 Lombardy ICU Network
Apr 14, 2020·Journal of the American Academy of Dermatology·Vito Di Lernia
Apr 16, 2020·Dermatologic Therapy·Lavinia Agra ColettoRoberto Caporali
Apr 18, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A Di AltobrandoF Bardazzi
Apr 28, 2020·Dermatologic Therapy·Matteo MegnaGabriella Fabbrocini
Apr 30, 2020·The British Journal of Dermatology·S K MahilUNKNOWN Secure-AD and PsoProtect study groups
Jul 9, 2020·Nature·Elizabeth J WilliamsonBen Goldacre
Aug 1, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·M TalamontiUNKNOWN PSO-BIO-COVID study group

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Citations

Mar 2, 2021·Frontiers in Medicine·Thomas GraierPeter Wolf
May 8, 2021·Italian Journal of Dermatology and Venereology·Luca StingeniUNKNOWN Board Members of SIDeMaST
Sep 13, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·K HanselL Stingeni
Oct 27, 2021·Expert Review of Clinical Immunology·Clara De SimoneFrancesca Prignano
Oct 18, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·Y LytvynJ Yeung
Oct 27, 2021·Dermatologic Therapy·Maria Letizia MusumeciGiuseppe Micali

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