Characteristics and management of giant cell arteritis in France: a study based on national health insurance claims data

Rheumatology
Alfred MahrEric Hachulla

Abstract

Few data are available on the epidemiology and management of GCA in real life. We aimed to address this situation by using health insurance claims data for France. This retrospective study used the Echantillon Généraliste de Bénéficiaires (EGB) database, a 1% representative sample of the French national health insurance system. The EGB contains anonymous data on long-term disease status, hospitalizations and reimbursement claims for 752 717 people. Data were collected between 2007 and 2015. The index date was defined as the date of the first occurrence of a GCA code. Demographics, comorbidities, diagnostic tests and therapies were analysed. Annual incidence rates were calculated, and incident and overall GCA cases were studied. We identified 241 patients with GCA. The annual incidence was 7-10/100 000 people ⩾50 years old. Among the 117 patients with incident GCA, 74.4% were females, with mean age 77.6 years and mean follow-up 2.2 years. After the index date, 51.3% underwent temporal artery biopsy and 29.1% high-resolution Doppler ultrasonography. Among the whole cohort, 84.3% used only glucocorticoids. The most-prescribed glucocorticoid-sparing agent was methotrexate (12.0%). The incidence of GCA in France is 7-10/100 000 peop...Continue Reading

References

Oct 15, 2003·Arthritis and Rheumatism·Anne ProvenGene G Hunder
Feb 21, 2008·Clinical Reviews in Allergy & Immunology·Jennifer L LeeM Eric Gershwin
Apr 17, 2008·Annals of the Rheumatic Diseases·C MukhtyarUNKNOWN European Vasculitis Study Group
Oct 1, 2009·Arthritis and Rheumatism·Miguel A Gonzalez-GayJavier Llorca
Apr 8, 2010·Rheumatology·Bhaskar DasguptaUNKNOWN BSR and BHPR Standards, Guidelines and Audit Working Group
Jul 6, 2010·Revue D'épidémiologie Et De Santé Publique·P TuppinY Merlière
Dec 21, 2011·Arthritis Care & Research·Madeleine Durand, Sara L Thomas
Mar 5, 2014·Annals of Internal Medicine·Gunnar TomassonPeter A Merkel
May 2, 2014·Journal of Neurology, Neurosurgery, and Psychiatry·Maxime SamsonYannick Béjot
Jul 6, 2014·The New England Journal of Medicine·Cornelia M Weyand, Jörg J Goronzy
Sep 7, 2014·Rheumatology·Francesco MuratoreKenneth J Warrington
Nov 5, 2014·The Journal of Rheumatology·Elisabeth De SmitAlex W Hewitt
Apr 1, 2015·Seminars in Arthritis and Rheumatism·Clement John MichetEric L Matteson
Apr 17, 2015·The Journal of Rheumatology·Tanaz A KermaniUNKNOWN Vasculitis Clinical Research Consortium
Feb 3, 2016·La Revue de médecine interne·B BienvenuUNKNOWN Groupe d’Étude Français des Artérites des gros Vaisseaux, under the Aegis of the Filière des Maladies Auto-Immunes et Auto-I
Jun 15, 2016·JAMA : the Journal of the American Medical Association·Frank ButtgereitBhaskar Dasgupta
Dec 7, 2016·Modern Rheumatology·Bénédicte WateletBoris Bienvenu
Jan 14, 2017·Rheumatology and Therapy·Joseph B BabigumiraLouis P Garrison
Jan 31, 2017·Arthritis & Rheumatology·Carol A LangfordUNKNOWN Vasculitis Clinical Research Consortium
May 4, 2017·The Journal of Rheumatology·Matthew J KosterKenneth J Warrington
Jul 27, 2017·The New England Journal of Medicine·John H StoneNeil Collinson
Oct 4, 2017·Arthritis Care & Research·Michael MouniéGrégory Pugnet
Jan 24, 2018·Annals of the Rheumatic Diseases·Christian DejacoWolfgang A Schmidt
Apr 6, 2019·Arthritis Care & Research·Sabine MainbourgJean-Christophe Lega

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Citations

Apr 7, 2020·Rheumatology·Lillian BarraJessica Widdifield
Jul 11, 2020·Joint, Bone, Spine : Revue Du Rhumatisme·Guillermo Carvajal AlegriaDivi Cornec
Dec 4, 2021·Frontiers in Medicine·Alfred MahrValérie Devauchelle-Pensec

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