Characteristics and Outcomes of Young Children Hospitalized with Laboratory-Confirmed Influenza or Respiratory Syncytial Virus in Ontario, Canada, 2009-2014

The Pediatric Infectious Disease Journal
Sarah A BuchanJeffrey C Kwong

Abstract

Respiratory illnesses are a major contributor to pediatric hospitalizations, with influenza and respiratory syncytial virus (RSV) causing substantial morbidity and cost each season. We compared the characteristics and outcomes of children 0-59 months of age who were hospitalized with laboratory-confirmed influenza or RSV between 2009 and 2014 in Ontario, Canada. We included hospitalized children who were tested for influenza A, influenza B, and RSV, and were positive for a single virus. We characterized individuals by their demographics and healthcare utilization patterns, and compared their hospital outcomes, in-hospital cost, and post-discharge healthcare use by virus type and by presence of underlying comorbidities. We identified and analyzed 7,659 hospitalizations during which a specimen tested positive for influenza or RSV. Children with RSV were the youngest whereas children with influenza B were the oldest (median ages 6 months [interquartile range {IQR}: 2-17 months] and 25 months [IQR: 10-45 months], respectively). Complex chronic conditions were more prevalent among children with all influenza (sub)types than RSV (31%-34% vs 20%). In-hospital outcomes were similar by virus type, but in children with comorbidities, pos...Continue Reading

References

Jan 29, 2000·The New England Journal of Medicine·H S IzurietaK Fukuda
Apr 28, 2005·Archives of Disease in Childhood·D M FlemingK W Cross
Jul 11, 2006·Journal of Clinical Epidemiology·Damon C ScalesDonald A Redelmeier
Nov 3, 2006·Pediatrics·Ron KerenSusan E Coffin
Jan 23, 2009·The Journal of Pediatrics·Geoffrey A WeinbergUNKNOWN New Vaccine Surveillance Network
Feb 7, 2009·The New England Journal of Medicine·Caroline Breese HallPeter Szilagyi
Nov 26, 2009·Pediatrics·Florence T BourgeoisKenneth D Mandl
Jun 26, 2010·Vaccine·Gerry FairbrotherUNKNOWN New Vaccine Surveillance Network (NVSN)
Jan 26, 2011·Clinical Pediatrics·Manika SuryadevaraJoseph B Domachowske
Jun 15, 2011·Influenza and Other Respiratory Viruses·Emily T MartinJanet A Englund
Aug 6, 2011·The Pediatric Infectious Disease Journal·Lauren J StockmanGayle Fischer-Langley
Oct 15, 2011·The Pediatric Infectious Disease Journal·Susan E CoffinTheoklis E Zaoutis
Oct 21, 2011·The Journal of Infectious Diseases·Marika K IwaneDean D Erdman
Nov 15, 2011·Journal of Paediatrics and Child Health·Hannah C MooreDeborah Lehmann
Apr 13, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hong ZhouDavid K Shay
Aug 31, 2012·Pediatrics·Dat TranUNKNOWN IMPACT investigators
Oct 2, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S KouniA Michos
Feb 15, 2013·The New England Journal of Medicine·Kathryn M EdwardsUNKNOWN New Vaccine Surveillance Network
May 8, 2014·Influenza and Other Respiratory Viruses·Sandra A AsnerMarek Smieja
Nov 2, 2014·BMC Infectious Diseases·Javier Díez-DomingoPablo Lázaro
Nov 12, 2014·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Marcelo L UrquiaUNKNOWN Canadian Curves Consortium
Aug 19, 2016·Pediatrics·Dat TranUNKNOWN members of the Canadian Immunization Monitoring Program Active
Oct 4, 2016·The Journal of Infectious Diseases·Janet A Englund, Helen Y Chu
Oct 16, 2016·The Journal of Infectious Diseases·Terho HeikkinenMatti Waris

❮ Previous
Next ❯

Citations

Nov 19, 2019·The Pediatric Infectious Disease Journal·Sonya C Tang GirdwoodJennifer M Kaplan
Dec 6, 2019·Journal of Medical Virology·Vitória Rodrigues Guimarães AlvesNancy Bellei

❮ Previous
Next ❯

Related Concepts