Characteristics and outcomes of cholangiocarcinoma by region in Thailand: A nationwide study

World Journal of Gastroenterology : WJG
Roongruedee ChaiteerakijKamthorn Phaosawasdi

Abstract

To identify the potential risk factors of cholangiocarcinoma, we determined the characteristics of cholangiocarcinoma patients among 5 different regions of Thailand. All patients diagnosed with cholangiocarcinoma between 2008 and 2013 were identified using the Nationwide Hospital Admission Data registry (n = 39421). Baseline characteristics, comorbidities and survival were abstracted. The annual incidence during the study period was stable in all regions. Most patients lived in the Northeast (62.8%), followed by the North (16.9%), Central (12.3%), Bangkok (5.4%), and South (n = 2.6%) regions (P < 0.0001). Significantly more cholangiocarcinoma patients had diabetes, cirrhosis, and chronic viral hepatitis B/C infection than non-cholangiocarcinoma participants (diabetes: 11.42% vs 5.28%; cirrhosis: 4.81% vs 0.92%; hepatitis B: 0.74% vs 0.12%; and hepatitis C: 0.50% vs 0.10%, P < 0.0001 for all, respectively). The overall 1-year mortality rate was 81.7%, with a stable trend over time. Diabetes and chronic liver diseases may be associated with cholangiocarcinoma in the Thai population.

References

Nov 13, 2003·Acta Tropica·P Jongsuksuntigul, T Imsomboon
Jul 12, 2007·PLoS Medicine·Banchob SripaPaul J Brindley
Jan 19, 2008·World Journal of Gastroenterology : WJG·Yan-Ming ZhouDian-Qi Li
Apr 15, 2008·Current Opinion in Gastroenterology·Banchob Sripa, Chawalit Pairojkul
Jun 19, 2008·The American Journal of Gastroenterology·Tae Y LeeDong J Suh
Dec 22, 2009·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Domenico AlvaroUNKNOWN AISF Cholangiocarcinoma committee
Jul 2, 2010·Journal of Korean Medical Science·Hai-Rim ShinSung-Tae Hong
Nov 9, 2010·Journal of Hepatology·Côme LepageAnne-Marie Bouvier
Apr 14, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gia L Tyson, Hashem B El-Serag
Aug 23, 2011·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Wei JingXiangui Hu
Jun 15, 2012·Journal of Gastroenterology and Hepatology·Min LiJianping Gong
Oct 12, 2012·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Roongruedee ChaiteerakijLewis R Roberts
Oct 22, 2013·Gastroenterology·Sumera Rizvi, Gregory J Gores
Aug 8, 2014·Acta Tropica·Banchob SripaBruce A Wilcox
Oct 8, 2014·Journal of Clinical Gastroenterology·Steven ScaglioneMichael L Volk
Mar 5, 2016·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jonggi ChoiLewis R Roberts

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Citations

Jul 9, 2020·Pathology International·Thiyaphat Laohawetwanit, Naruemon Klaikaew
Oct 5, 2019·Scientific Reports·Apiporn T SuwannatraiKinley Wangdi
Oct 2, 2020·Biomolecules·Yu-Chan ChangMichael Hsiao
Dec 29, 2020·World Journal of Gastrointestinal Oncology·Chi-Chih WangMing-Chang Tsai
Nov 22, 2020·Canadian Journal of Diabetes·Charupong SaengboonmeeSopit Wongkham

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