Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA).

ISRN Pharmacology
Priyanka P BrahmkshatriyaRamesh K Goyal

Abstract

Diabetes, one of the most commonly seen metabolic disorders, is affecting a major area of population in many developing as well as most of the developed countries and is becoming an alarming concern for the rising cost of the healthcare system. Latent Autoimmune Diabetes in Adults (LADA) is a form of diabetes which is less recognized and underdiagnosed type of diabetes which appears to have characteristics of both type 1 (autoimmune in nature) and type 2 diabetes (adult age at onset and initial response to oral hypoglycemic agents). An epidemiological study was carried out on 500 patients in the western region of India. Various parameters such as age at onset, duration of diabetes, gender, basal metabolic index (BMI), type of diabetes, family history, HbA1c levels, cholesterol levels, and current treatment regimen were evaluated and correlated with type 1 and type 2 diabetes. Moreover, diagnostic markers for LADA, namely, GAD autoantibodies and C-peptide levels, were determined for 80 patients selected from the epidemiological study. Some of the results obtained were found to be consistent with the literature whereas some results were found to be contradictory to the existing data.

References

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Jan 27, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Georg BiesenbachUNKNOWN Diabetic Nephropathy Study Group of the Austrian Society of Nephrology
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Citations

Apr 23, 2014·Clinical Reviews in Allergy & Immunology·Zhiguo XieZhiguang Zhou
Apr 29, 2014·Emergency Medicine Clinics of North America·Omoyemi Adebayo, George C Willis
Feb 16, 2017·Diabetes/metabolism Research and Reviews·Alok Kumar, Alberto de Leiva
Nov 24, 2016·Clinical Reviews in Allergy & Immunology·Zhen WangZhiguang Zhou
Oct 30, 2018·International Journal of Dentistry·Lulëjeta FeriziVjosa Kotori
Jun 5, 2021·Clinical Case Reports·Gabriela Sobreira PereiraJorge Cotter
Jun 15, 2021·International Immunopharmacology·Shabnam RadbakhshAmirhossein Sahebkar

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Methods Mentioned

BETA
ELISA
genotyping

Software Mentioned

LADA
GraphPad

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