Characteristics and prognosis of hearing loss associated with Vogt-Koyanagi-Harada disease

Audiology & Neuro-otology
Shinya MoritaSatoshi Fukuda

Abstract

To clarify the characteristics and prognosis of hearing loss associated with Vogt-Koyanagi-Harada (VKH) disease. We retrospectively examined 85 patients diagnosed with VKH disease between January 1996 and December 2012. The control group included age- and gender-matched individuals without definitive ear disease. The patients with VKH disease were treated with high-dose systemic corticosteroids, which were tapered off gradually over a period of 6 months or more by the treating ophthalmologists according to the severity of the ocular inflammation. The features of hearing loss were analyzed based on pure tone audiometric data obtained at the initial presentation according to diagnostic criteria based on the ISO 7029 standard. The efficacy of corticosteroid therapy was evaluated by audiometry at the initial presentation and during therapy for 3-6 months. In patients with VKH disease, the rate of hearing loss detected by audiometry was significantly higher than that of either subjective hearing loss (p < 0.001) or tinnitus (p < 0.001). Bilateral symmetrical hearing loss was the most common type of auditory disturbance associated with VKH disease. The degree of hearing loss was generally low, with no patients showing profound hearin...Continue Reading

Citations

Oct 31, 2017·Audiology & Neuro-otology·Keishi FujiwaraAkihiro Homma
Jun 21, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Nora AlHelaliAbdulrahman Hagr
Mar 11, 2019·Journal of Neurology, Neurosurgery, and Psychiatry·James D TriplettTodd A Hardy
Mar 21, 2017·Advances in Therapy·Dana M HartlJean-Charles Soria
Jul 12, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Charlotte W DuinkerkenCharlotte L Zuur

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