Characteristics and prognostic factors of synchronous multiple primary esophageal carcinoma: A report of 52 cases

Thoracic Cancer
Mei Li, Zhi-Xiong Lin

Abstract

To retrospectively analyze the clinical characteristics and prognostic factors of 52 cases of synchronous multiple primary esophageal carcinoma (SMPEC), in order to provide a reference for treatment strategy. Clinical and survival data of 52 patients with SMPEC were analyzed retrospectively. The rates of overall survival (OS), depending on the different factors, were calculated using Kaplan-Meier analysis. A log-rank test was used for univariate survival analysis and Cox's proportional hazards regression model was used for multivariate survival analysis. Clinical and survival data of 52 patients with SMPEC, hospitalized from 1 January 2003 to 31 October 2011, were analyzed. Twelve patients underwent surgical resection, five received adjuvant radiotherapy and one received adjuvant radiochemotherapy. Thirty-seven of the 40 non-operative patients received external beam radiation therapy and 20 of them received platinum-based chemotherapy. Another three non-operative patients were given platinum-based chemotherapy alone. The one, three, and five-year OS and the median survival time (MST) were 65.4%, 17.3%, 7.7%, respectively, and 15.0 months for the whole cohort. Tumor length and M stage were independent prognostic factors for the ...Continue Reading

Citations

Jun 19, 2019·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Di SunPing-Hong Zhou
May 11, 2018·The Korean Journal of Internal Medicine·Zhiqin ChenGuang Li

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