Characteristics and survival data from Latvian pulmonary hypertension registry: comparison of prospective pulmonary hypertension registries in Europe

Pulmonary Circulation
Andris SkrideIrene Lang

Abstract

Patient registries are a valuable tool in the research of rare conditions such as pulmonary hypertension (PH). We report comprehensive hemodynamic and survival data of 174 patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), included in the prospective Latvian PH registry over a period of > 9 years. In total, 130 adult PAH patients (75%) and 44 adult CTEPH patients (25%) were enrolled. The median follow-up period was 33 months for PAH and 18 months for CTEPH, P = 0.001. Latvian CTEPH patients had significantly higher plasma levels of B-type natriuretic peptide, higher pulmonary vascular resistance, and lower cardiac index than Latvian PAH patients. Calculated incidence of PAH and CTEPH in Latvia in 2016 was 13.7 and 5.1 cases per million inhabitants, calculated prevalence was 45.7 and 15.7 cases per million inhabitants, respectively. Survival rates at one, three, and five years for PAH patients was 88.0%, 73.3%, and 58.1%, and 83.8%, 59.0%, and 44.2% for CTEPH patients, respectively. We compared our study results with data from European adult PH registries. Latvian PAH patients had the fourth lowest and CTEPH patients the lowest one-year survival rate among European adul...Continue Reading

References

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Citations

Jan 18, 2019·Medicina·Matiss SablinskisAndris Skride
Jun 17, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Abdullah M AldalaanNadeen Alharbi
Oct 31, 2019·Pulmonary Circulation·Alexandra ArvanitakiUNKNOWN Hellenic Society for the Study of Pulmonary Hypertension (HSSPH)
Apr 2, 2020·Expert Opinion on Pharmacotherapy·Ioana A Campean, Irene M Lang
Sep 22, 2020·Respirology : Official Journal of the Asian Pacific Society of Respirology·Limin DengJianguo He
Feb 6, 2021·Clinics in Chest Medicine·Hannah MorrisMargaret R MacLean
Jul 14, 2020·Revista Española De Cardiología·Paula Martínez-SantosUNKNOWN REHAP investigators

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Methods Mentioned

BETA
RAP

Software Mentioned

COMPERA
PH
SPSS Statistics
Gi
Reg
REHAP

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