Characteristics at the time of oxygen initiation associated with its adherence: Findings from the COPD Long-term Oxygen Treatment Trial

Respiratory Medicine
Marilyn L MoyLOTT Research Group

Abstract

Characteristics associated with adherence to long-term oxygen therapy (LTOT) in COPD remain unclear. To identify patient characteristics at the time of oxygen initiation associated with its adherence. We conducted a secondary analysis of data from 359 COPD participants assigned to oxygen in the Long-term Oxygen Treatment Trial. Participants were prescribed continuous (n = 214) or intermittent (n = 145) oxygen based on desaturation patterns at study entry. At the time of initial prescription, participants rated their perceived readiness, confidence, and importance to use oxygen on a 0-10 scale (0 = not at all, 10 = very much). During follow-up, they self-reported average hours per day of use (adherence). Adherence was averaged over short-term (0-30 days), medium-term (months 9-12), and long-term (month 13 to last follow-up) intervals. Multivariable logistic regression models explored characteristics associated with high adherence (≥16 h/day [continuous] or ≥8 h/day [intermittent]) during each time interval. Participant readiness, confidence, and importance at the time of oxygen initiation were associated with high short- and medium-term adherence. For each unit increase in baseline readiness, the odds of high short-term adherenc...Continue Reading

Associated Clinical Trials

References

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Oct 27, 2016·The New England Journal of Medicine·UNKNOWN Long-Term Oxygen Treatment Trial Research GroupWilliam Bailey
Nov 1, 2017·Annals of the American Thoracic Society·Roger D YusenUNKNOWN LOTT Research Group
Mar 17, 2018·American Journal of Respiratory and Critical Care Medicine·Yves LacasseJerry A Krishnan

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Citations

Dec 9, 2020·Pneumologie·P HaidlUNKNOWN Deutsche Sauerstoff- und BeatmungsLiga LOT e. V.

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