Characteristics, impact and treatment of 6000 headache attacks: the PAMINA study

European Journal of Pain : EJP
Doris Lieba-SamalPAMINA-Study Group

Abstract

The aim of this study was to prospectively evaluate the characteristics of headache attacks, their impact on daily activities as well as the type and efficacy of acute medication in patients with migraine. We included 281 patients with episodic migraine (87% females, aged 41.2±12.1). All patients kept a headache diary for 3 months covering headache characteristics, therapy and questions adopted from the Headache Impact Test (HIT-6) for rating the impact of each single headache attack (HIT-6s). For evaluating the efficacy of acute medication we compared triptans with other compounds using headache duration as outcome parameter. Of 6051 headache attacks 52.8% fulfilled the ICHD-II criteria of migraine. The HIT-6s score was 2.4±2.2 (range 0-6). It was lowest in untreated headaches (2.0±2.1) and highest in those treated with a combination of triptans and other compounds (4.1±2.0, p<0.001). Patients used triptans on 8.0% of all headache days, other compounds on 33.1%, a combination of both on 1.5% and no medication on 57.3% of the headache days. Migraine attacks of moderate or severe intensity treated with triptans alone lasted significantly shorter than those treated with other compounds (5.1±3.6 vs. 6.9±5.3h, p<0.001). In conclusi...Continue Reading

References

Aug 1, 1992·Cephalalgia : an International Journal of Headache·B K Rasmussen, J Olesen
Apr 1, 1994·Cephalalgia : an International Journal of Headache·M B RussellJ Olesen
Nov 22, 2000·JAMA : the Journal of the American Medical Association·R B LiptonUNKNOWN Disability in Strategies of Care Study group
May 16, 2002·Neurology·R B LiptonC Hall
Jul 23, 2002·Cephalalgia : an International Journal of Headache·D ColognoG C Manzoni
Aug 30, 2003·Clinical Therapeutics·Maria Angeles Ceballos HernansanzUNKNOWN START 10 Study Group
Mar 5, 2004·Pharmacoepidemiology and Drug Safety·Darren M Ashcroft, David Millson
Apr 21, 2004·Cephalalgia : an International Journal of Headache·R B LiptonP J Goadsby
Sep 24, 2004·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M K EriksenJ Olesen
Nov 19, 2004·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·M C NarboneS Gangemi
Jan 22, 2005·Cephalalgia : an International Journal of Headache·S W HamelskyW F Stewart
Feb 12, 2005·Headache·Luis E MorilloUNKNOWN Latin American Migraine Study Group
Mar 19, 2005·Cephalalgia : an International Journal of Headache·C LucasM Lantéri-Minet
May 10, 2005·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Patrik Andlin-SobockiJes Olesen
Nov 25, 2005·Cephalalgia : an International Journal of Headache·M Lantéri-MinetC Lucas
May 31, 2006·Headache·Leslie Kelman
Nov 23, 2006·Headache·William Pryse-PhillipsKeith Wilson
Feb 1, 2007·Cephalalgia : an International Journal of Headache·S SilbersteinUNKNOWN AMPP Advisory Group
Mar 23, 2007·Cephalalgia : an International Journal of Headache·C WöberUNKNOWN PAMINA Study Group
Mar 27, 2007·Cephalalgia : an International Journal of Headache·Lj StovnerJ-A Zwart
Jul 20, 2007·The Cochrane Database of Systematic Reviews·A D OldmanR A Moore
Jul 20, 2007·The Cochrane Database of Systematic Reviews·L A SmithR A Moore
Sep 9, 2009·Cephalalgia : an International Journal of Headache·D Lieba-SamalC Wöber

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Citations

May 17, 2011·Current Pain and Headache Reports·Doris Lieba-Samal, Christian Wöber
Oct 24, 2012·Wiener klinische Wochenschrift·Doris Lieba-SamalChristian Wöber
Apr 26, 2017·Cephalalgia : an International Journal of Headache·Maria-Eliza R AguilaAndrew M Leaver

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