PMID: 8942896Nov 1, 1996Paper

Characteristics influencing outcomes of excimer laser photorefractive keratectomy. Summit Photorefractive Keratectomy Phase III Study Group

Ophthalmology
P S HershR F Steinert

Abstract

To identify preoperative and intraoperative characteristics associated with outcomes of photorefractive keratectomy (PRK). In the phase III multicenter clinical trials of the Summit Technology excimer laser for corrections of 1.5 to 6.0 diopters (D) of myopia, three principal outcomes of PRK on 612 patients were examined: (1) uncorrected visual acuity of 20/40 or better, (2) predictability of refractive outcome within 1.0 D of attempted correction, and (3) stability of refractive result between 12 and 24 months. Multiple logistic regression was used to test for independent associations of multiple preoperative and intraoperative characteristics with each of these outcomes. Older age was independently associated with lesser likelihood of achieving 20/40 or better uncorrected visual acuity (odds ratio = 1.08 per incremental year of age, 95% confidence interval [CI] = 1.04-1.12) and with decreased predictability, specifically with overcorrection (odds ratio = 1.09, 95% CI = 1.06-1.12), but age was not associated with stability of refraction. Greater attempted correction was associated independently with a decreased likelihood of 20/40 or better uncorrected visual acuity (odds ratio = 2.78 for corrections of 3.5-5.5 D, 95% CI = 1.1...Continue Reading

References

Oct 1, 1991·Archives of Ophthalmology·W C WuW R Green
Jan 1, 1988·Journal of Cataract and Refractive Surgery·C R MunnerlynJ Marshall
Nov 1, 1985·Archives of Ophthalmology·R R Krueger, S L Trokel
Dec 1, 1983·American Journal of Ophthalmology·S L TrokelB Braren
Oct 1, 1994·Archives of Ophthalmology·G O WaringP J McDonnell
Nov 1, 1994·Archives of Ophthalmology·S DuttC A Puliafito
Sep 1, 1994·Ophthalmology·N A SherJ M Frantz
Mar 15, 1994·American Journal of Ophthalmology·L J Maguire

❮ Previous
Next ❯

Citations

Aug 1, 1997·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·P O Denk, M Knorr
Jan 20, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M MrochenT Seiler
Sep 27, 2000·American Journal of Ophthalmology·W W Haw, E E Manche
Apr 12, 2003·Ophthalmology·Peter S HershDouglas S Bishop
Dec 17, 1998·Ophthalmology·S ShahR J Smith
Feb 28, 2001·Journal of Cataract and Refractive Surgery·S K RaoD S Lam
Mar 14, 2000·Journal of Cataract and Refractive Surgery·E M FisherP S Hersh
Apr 20, 2000·Journal of Cataract and Refractive Surgery·S N RaoP J McDonnell
Nov 1, 2002·International Ophthalmology Clinics·Robert W ThompsonFrancis W Price
Jan 23, 2008·International Ophthalmology Clinics·Gaston O Lacayo, J Bradley Randleman
Apr 17, 2002·Journal of Cataract and Refractive Surgery·Sunil ShahRonald J Smith
Sep 17, 2002·Journal of Cataract and Refractive Surgery·Rosario Cobo-SorianoJulio Baviera
Aug 23, 2001·Journal of Biomedical Optics·D CohenW Grundfest
Jul 31, 1998·The Western Journal of Medicine·E E MancheP S Hersh
May 24, 2008·Journal of Cataract and Refractive Surgery·Laura de Benito-LlopisRaquel Gil-Cazorla
Dec 23, 2015·Journal of Ophthalmology·Engy Mohamed Mostafa
Jan 18, 2006·Journal of Cataract and Refractive Surgery·Irene C KuoNada S Jabbur
Mar 12, 2016·Cornea·Michael MimouniIgor Kaiserman
Mar 4, 2014·Journal of Cataract and Refractive Surgery·Elizabeth M HofmeisterSteve C Schallhorn
Jul 31, 1998·Journal of Cataract and Refractive Surgery·S H YangJ S Pepose
Aug 21, 2020·Translational Vision Science & Technology·Yu-Chi LiuJodhbir S Mehta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.