Characteristics of a new epidemic MRSA in Germany ancestral to United Kingdom EMRSA 15

International Journal of Medical Microbiology : IJMM
W WitteD Heuck

Abstract

In 1996 a new epidemic MRSA emerged in three hospitals North of Berlin. This strain, Barnim epidemic MRSA, was isolated in 15 hospitals in Northern Germany in 1997 and 29 hospitals throughout Germany in 1998. Isolates of this clone are non-typeable by phages, its resistance phenotype is PEN, OXA, ERY, CLI, CIP (genotype: mecA, ermC, mutations in grlA and gyrA). The Sma I macrorestriction pattern corresponds to particular phage group II strains which is confirmed by the 16S-23S rRNA gene spacer pattern. Isolates of this clone differ by less than three Sma I macrorestriction fragments from isolates of the EMRSA15 clone from the United Kingdom, the most common epidemic MRSA isolates in the United Kingdom in recent years. Both epidemic strains produce enterotoxin C and possess the sec determinant for this toxin, the configuration of the mec regulon is mecI-, mecRB+, mecRC+. Both share the same Alu I pattern of PCR amplimers of the 3' end region of the coagulase gene. EMRSA 15 and Barnim EMRSA share a common multilocus sequence type indicating a recent, shared evolutionary origin.

References

Aug 1, 1988·Journal of Medical Microbiology·M A Beard-PeglerA M Vickery
Feb 1, 1995·The Journal of Hospital Infection·R R MarplesB D Cookson
Apr 9, 1998·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·H ClausW Witte

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Citations

Jun 3, 2005·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B GhebremedhinB König
Feb 28, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A S RossneyB O'Connell
Nov 17, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E A SciclunaS Monecke
Apr 23, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A TavaresUNKNOWN CA-MRSA/MSSA working group
Mar 2, 2002·The Lancet Infectious Diseases·S HarbarthJ Huebner
Apr 12, 2002·The Lancet Infectious Diseases·Duarte C OliveiraHermínia de Lencastre
May 24, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Li-Yang HsuBan-Hock Tan
Apr 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lona ModySuzanne F Bradley
Nov 23, 2007·Journal of Clinical Microbiology·B StrommengerW Witte
Nov 1, 2002·Journal of Clinical Microbiology·C L C WieldersF J Schmitz
Nov 8, 2003·Journal of Clinical Microbiology·O MelterH de Lencastre
Oct 9, 2004·Journal of Clinical Microbiology·Eduardo Pérez-RothSebastián Méndez-Alvarez
Oct 18, 2008·Journal of Medical Microbiology·Simon W J GouldMark D Fielder
Nov 25, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kristen E GibsonLona Mody
Feb 5, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·D A Robinson, M C Enright
Feb 18, 2003·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A van Belkum
Feb 20, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·E BoakesM J Ellington
Aug 21, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A N PintoM V N O'Sullivan
Oct 24, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S MoneckeR Ehricht
Apr 1, 2008·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S MoneckeR Ehricht
Oct 26, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Abiola SenokStefan Monecke
Feb 15, 2002·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·W WitteM Kresken
Dec 15, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Bushra JamilStefan Monecke
Feb 2, 2002·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·D C OliveiraH de Lencastre
Sep 24, 2004·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·O MelterH de Lencastre

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