PMID: 45244Feb 15, 1979

Characteristics of a rat liver cellular extract protein which mediates transport of various phospholipids from liposomes to mitochondria

Bollettino della Società italiana di biologia sperimentale
F M RuggieroC Landriscina

Abstract

The effect of pH, Ca++ and Na+ concentration on the phosphatidylethanolamine transport from liposomes to mitochondria by an aspecific soluble rat liver protein has been studied. Results obtained indicate that at pH higher than 6.5 and Ca++ ion concentrations from 5 mM on the transport is strongly inhibited. Preliminary data with ESR spectrometry concerning the nature of lipoprotein association between phosphatidylethanolamine and carrier protein during the transport are also presented.

Related Concepts

Calcium
Phospholipid scramblase
Mitochondria, Liver
Phosphatidylethanolamine
Soluble
Mitochondria
Sodium
Lipoproteins
Phospholipids
Niosomes

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