Characteristics of COPD smokers and effectiveness and safety of smoking cessation medications

Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco
Carlos A Jiménez RuizGema Lopez Gonzalez

Abstract

Smoking is the main cause of chronic obstructive pulmonary disease (COPD), and smoking cessation is the only treatment shown to be effective in arresting the progression of COPD. Different epidemiological and population-based studies have shown smokers with COPD to have specific smoking characteristics that differentiate them from the rest of smokers and which complicate smoking cessation. The main objective of this study is to analyze the effectiveness and safety of drug treatments for smoking cessation in smokers with severe or very severe COPD. Smokers with severe or very severe COPD (Global Initiative for Chronic Obstructive Lung Disease stages III and IV) received treatment for smoking cessation. The treatment program consisted of a combination of behavioral therapy and drug treatment. Patients were followed up at 1, 2, 4, 6, 8, 10, 12, 18, and 24 weeks after the quit date. Four hundred seventy-two patients were seen, 65% were male, and their mean age was 58.3 (9.8). They smoked an average of 29.7 (13.4) cigarettes/day, and their mean Fagerström test for nicotine dependence score was 7.4 (2.1). Continuous abstinence rate from 9 to 24 weeks (CAR 9-24) was 48.5%. According to type of treatment used, CAR 9-24 for nicotine rep...Continue Reading

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Citations

May 7, 2013·Archivos de bronconeumología·Carlos A Jiménez-RuizUNKNOWN Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Aug 21, 2015·Wiener medizinische Wochenschrift·Gerhard Hamilton, Barbara Rath
Dec 17, 2014·Revue des maladies respiratoires·M UndernerG Peiffer
Feb 25, 2014·Respiratory Medicine·Ch GratziouS Zakynthinos
Aug 10, 2012·British Journal of Community Nursing·Maria Duaso, Debbie Duncan
Apr 18, 2015·The European Respiratory Journal·Carlos A Jiménez-RuizChristina Gratziou
Jun 1, 2014·American Journal of Physiology. Lung Cellular and Molecular Physiology·Li ZuoThomas M Best
Feb 14, 2020·Current Medical Research and Opinion·Serena TonstadCristina Russ
Dec 30, 2020·Expert Opinion on Pharmacotherapy·Sabina Antonela AntoniuAntigona Carmen Trofor
Apr 9, 2021·The Clinical Respiratory Journal·Hulya Sahin, Ilknur Naz

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