Characteristics of eight X-STR loci for forensic purposes in the Chinese population.

International Journal of Legal Medicine
Hai-bo LuoYi-ping Hou

Abstract

X-chromosomal short tandem repeats (ChrX STRs) loci are used for forensic practice in recent years. Considering the unique heredity characteristics of ChrX, recombination and linkage disequilibrium (LD) among ChrX STR loci vary between male and female and different populations as well. However, there is a lack of data for analysis of recombination and linkage disequilibrium on ChrX STR loci in the Chinese population. In this work, a total of 303 unrelated individuals (203 males and 100 females) in the Chinese Han population were analyzed with Mentype Argus X-8 PCR amplification kit (DXS10135-DXS8378, DXS7132-DXS10074, HPRTB-DXS10101, and DXS10134-DXS7423). The recombination and linkage disequilibrium of the eight ChrX STR loci were investigated with HapMap LD plots and software ARLEQUIN 3.1. Allele frequencies of the eight loci and further population forensic genetic parameters were obtained. Our results revealed hotspots for recombination, and there was no obvious evidence for LD among the eight loci in the Chinese population. Our work implied that single locus frequencies rather than haplotype frequencies should be applied for forensic practice in the Chinese population.

References

Sep 24, 2002·Forensic Science International : Synergy·María T ZarrabeitiaJosé A Riancho
Apr 12, 2003·International Journal of Legal Medicine·R SziborD Krause
May 3, 2003·Genome Research·Rebecca C J TwellsJohn A Todd
Aug 14, 2003·American Journal of Human Genetics·Jeffrey D Wall, Jonathan K Pritchard
Jun 7, 2005·Forensic Science International : Synergy·Witold PepinskiIreneusz Soltyszewski
Aug 13, 2005·International Journal of Legal Medicine·Reinhard SziborJeanett Edelmann
Sep 1, 2005·International Journal of Legal Medicine·Reinhard SziborJeanett Edelmann
Jun 26, 2007·Forensic Science International : Synergy·Andrea ZalánHorolma Pamjav
Dec 17, 2008·International Journal of Legal Medicine·Leonor GusmãoAntónio Amorim
Jun 1, 2007·Forensic Science International. Genetics·Reinhard Szibor
Dec 17, 2008·Forensic Science International. Genetics·Jeanett EdelmannReinhard Szibor
Dec 17, 2008·Forensic Science International. Genetics·Dorit BeckerWerner Brabetz
Dec 17, 2008·Forensic Science International. Genetics·Andreas O TillmarKerstin Montelius
Jan 10, 2009·International Journal of Legal Medicine·Hsiao-Lin HwaTsang-Ming Ko
May 30, 2009·Croatian Medical Journal·Eun Jin LimKyoung-Jin Shin

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Citations

Oct 23, 2010·International Journal of Legal Medicine·Qiu-Ling LiuYe-Fei Chen
Feb 22, 2012·International Journal of Legal Medicine·Qiu-Ling LiuLi Quan
Jun 19, 2013·Croatian Medical Journal·Branka GrškovićGordan Mršić
Sep 3, 2011·International Journal of Legal Medicine·Carmen TomasNiels Morling
Sep 16, 2011·International Journal of Legal Medicine·Michinaga SamejimaKiyoshi Minaguchi
May 16, 2012·International Journal of Legal Medicine·Michinaga SamejimaKiyoshi Minaguchi
Mar 23, 2012·Forensic Science International. Genetics·Chengtao LiShilin Li
May 3, 2015·Forensic Science International. Genetics·Toni M Diegoli
Dec 26, 2012·Forensic Science International. Genetics·Jie XuBin Cong
May 5, 2016·Journal of Zhejiang University. Science. B·Yu-Xin GuoBo-Feng Zhu
Jan 20, 2017·International Journal of Legal Medicine·Chuncao DengYingbi Li
Apr 12, 2014·Electrophoresis·Hao-Tian MengXing Wei
Dec 23, 2011·Molecular Biology Reports·Suhua ZhangChengtao Li
Jul 22, 2017·International Journal of Legal Medicine·James Chun-I LeeHsing-Mei Hsieh

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