Characteristics of Esophageal Cancer Cases in Tanzania

Journal of Global Oncology
Elia J MmbagaKatherine Van Loon

Abstract

Age-standardized incidence rates for esophageal cancer (EC) in East Africa have been reported as disproportionately high compared with the worldwide incidence of nine per 100,000 population. This study aimed to characterize EC cases seen at Muhimbili National Hospital and Ocean Road Cancer Institute in Dar es Salaam, Tanzania. Demographic, clinical, and treatment variables were abstracted from charts of patients who received care for a diagnosis of EC at one or both institutions between 2011 and 2013. Categorical data were summarized as frequency counts and percentages. Continuous data were presented as medians and ranges. To compare men and women, Pearson's χ2 and two-sample t tests were applied. Seven hundred thirty-eight unique cases of EC were identified, of whom 68% were men and the median age was 60 years (range, 19 to 95 years). Notably, 93 cases (13%) were ≤ 40 years old at diagnosis. Squamous cell carcinoma was the dominant histology, comprising 90% of cases with documented histopathology. However, 34% of cases with a diagnosis of EC were not pathologically confirmed. The stage was documented as locoregional in 4% of cases, locally advanced in 20% of cases, metastatic in 14% of cases, and unknown in 63% of cases. Of 43...Continue Reading

References

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Citations

Sep 10, 2019·World Journal of Gastroenterology : WJG·Akwi W AsombangKulwinder S Dua
Sep 5, 2020·Implementation Science Communications·Rebecca J DeBoerKatherine Van Loon
Jun 16, 2021·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Khadija MsamiAmr S Soliman

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Methods Mentioned

BETA
biopsies
biopsy

Software Mentioned

R
Electronic Data Capture
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