PMID: 11920507Mar 29, 2002Paper

Characteristics of indolent non-Hodgkin lymphoma in patients with type 1 human immunodeficiency virus infection

Cancer
Alexandra M LevineBharat Nathwani

Abstract

There is recent evidence that the incidence of indolent non-Hodgkin lymphoma (NHL) appears to be increased in persons with the acquired immunodeficiency syndrome (AIDS). The current study was conducted to describe the clinical, immunologic, and pathologic characteristics of indolent B-cell lymphoma in patients infected with the human immunodeficiency virus (HIV). The current report was a retrospective study of 10 cases of indolent NHL identified from the AIDS-Lymphoma Registry at the University of Southern California School of Medicine. These patients were compared with 336 consecutive patients with systemic intermediate/high-grade AIDS-related NHL who were diagnosed and treated at a single institution. The pathology of the indolent cases included follicular lymphoma (five patients), small lymphocytic lymphoma (two patients), and one case each of mucosa-associated lymphoid tissue (MALT), monocytoid B-cell, and marginal zone lymphoma. When comparing the indolent lymphomas with the intermediate/high-grade AIDS-NHL cases, no differences were observed with regard to demographic characteristics or history of prior opportunistic infection. HIV patients with indolent lymphomas were found to have a significantly higher median CD4+ lymp...Continue Reading

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Citations

Aug 19, 2008·Annals of Hematology·Luca ArcainiMarco Paulli
May 1, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fumihiko Ishimaru
Dec 23, 2004·European Journal of Haematology·Thomas GirardFrançois Boué
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