Characteristics of Infectious Keratitis in Old and Very Old Patients

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Koji ToriyamaAtsushi Shiraishi

Abstract

The aim of this study was to analyze patient backgrounds, including activities of daily living (ADL) and living status, predisposing risk factors, causative agents, and severity with infectious keratitis in old (75 < 85 years of age) and very old (≥85 years of age) patients. We retrospectively reviewed 54 old patients who were hospitalized for infectious keratitis. The focus occupancy ratio (FOR) was defined as the total focus area/entire cornea area. The mean patient age was 82.9 ± 5.6 years. There were 33 old and 21 very old patients. Dementia was found in 8 patients (14.8%), but the most common predisposing risk factor was post-keratoplasty (15 patients, 27.8%). However, 10 patients (18.5%) had unknown risk factors. In all, 16 patients (29.6%) had low ADL, including being bedridden or being unable to go outside without assistance, and 19 patients (35.2%) lived alone. Causative agents were detected in 31 patients (57.4%) and included bacteria in 22 patients and fungi in 9 patients. Seventeen patients (31.5%) had >25% focus size of the corneal area. The average FOR was 12.1% ± 14.1%, and the mean best-corrected visual acuity (BCVA) at the first and final visits was 1.88 ± 0.71 and 1.52 ± 1.03 logMAR, respectively. Multivariate...Continue Reading

References

Jul 1, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Dale W BratzlerUNKNOWN Surgical Infection Society
Apr 19, 2005·The British Journal of Ophthalmology·T K H ButlerK McClellan
Mar 29, 2006·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Keizo SakamotoHiroshi Yamamoto
Oct 12, 2011·Archives of Ophthalmology·Muthiah SrinivasanUNKNOWN Steroids for Corneal Ulcers Trial Group
Oct 31, 2015·Investigative Ophthalmology & Visual Science·Naoko OkaYuichi Ohashi

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