PMID: 6697684Jan 1, 1984

Characteristics of pancreatic branched chain amino acid aminotransferases from rat, man and dog

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
M MakinoR Kido


Branched chain amino acid aminotransferase (EC from pancreas of rat, man and dog was highly purified and characterized. Rat pancreas contained only one type of branched chain amino acid aminotransferase, but human and dog pancreas contained two types. These were named Enzyme I and Enzyme III according to the classification by Aki et al. (1969). Five enzymes purified were activated by the addition of 2-mercaptoethanol and glutathione. Enzyme III has lower Km values for amino acids and 2-oxo acids than Enzyme I. Some other properties of purified enzymes are described.


May 1, 1976·Hoppe-Seyler's Zeitschrift für physiologische Chemie·T Noguchi, R Kido
Dec 15, 1975·Biochemical and Biophysical Research Communications·A IchiharaM Goto
Feb 11, 1970·Biochimica Et Biophysica Acta·Y NakataniK Higashino
Mar 1, 1969·The Journal of Clinical Investigation·P FeligG F Cahill

Related Concepts

Branched-chain-amino-acid aminotransferase
Enzymes, antithrombotic
Amino Acids, I.V. solution additive
Benign Tumor of Pancreas
Sulfhydryl Compounds
Glutathione Measurement
Substrate Specificity
Protein Conformation

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