Characteristics of polycystic ovary syndrome throughout life

Therapeutic Advances in Reproductive Health
Yvonne V Louwers, Joop S E Laven

Abstract

Polycystic ovary syndrome is the most common endocrine disorder in women of reproductive age. It is a complex disease in which genetic, endocrine, environmental, and behavioral factors are intertwined, giving rise to a heterogeneous phenotype with reproductive, metabolic, and psychological characteristics. Polycystic ovary syndrome affects women's health and their quality of life across the life course. During different life stages, the polycystic ovary syndrome phenotype can change, which requires a personalized diagnostic approach and treatment. Polycystic ovary syndrome is a major cause of anovulatory infertility; this disorder is also associated with hirsutism and acne. Diagnosing polycystic ovary syndrome during adolescence is challenging because the polycystic ovary syndrome criteria include normal physiological events that occur during puberty. With increasing age, the syndrome evolves from a reproductive disease to a more metabolic disorder. Along with metabolic disturbances, including insulin resistance and abnormalities of energy expenditure, polycystic ovary syndrome is recognized as a major risk factor for the development of type 2 diabetes and cardiovascular disease in later life. Moreover, there is evidence for fa...Continue Reading

References

Nov 1, 1984·Annals of Human Biology·D FlugA Prader
Feb 1, 1982·The Journal of Clinical Endocrinology and Metabolism·T Lemarchand-BéraudI Rey
May 1, 1983·The Journal of Endocrinology·M G MetcalfJ A Mackenzie
Dec 23, 2003·Human Reproduction·UNKNOWN Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
Feb 7, 2004·The Journal of Clinical Endocrinology and Metabolism·R AzzizL R Boots
Jun 10, 2005·The Journal of Clinical Endocrinology and Metabolism·Ricardo AzzizPaul Song
Aug 5, 2006·Clinical Endocrinology·T M BarberS Franks
Aug 8, 2006·Human Reproduction Update·C M BoomsmaN S Macklon
Oct 11, 2007·The Journal of Clinical Endocrinology and Metabolism·Bulent O YildizRicardo Azziz
Dec 7, 2007·The Journal of Clinical Endocrinology and Metabolism·Olivier ValkenburgJoop S E Laven
Aug 30, 2008·The Medical Clinics of North America·Maryse BrassardJean-Patrice Baillargeon
Feb 26, 2009·The Journal of Clinical Endocrinology and Metabolism·Monica MortensenRobert L Rosenfield
Jul 2, 2009·Human Reproduction Update·Bulent O YildizRicardo Azziz
Apr 2, 2010·Human Reproduction·J E de NietJ S E Laven
Jul 17, 2010·Seminars in Cutaneous Medicine and Surgery·Sheila F FriedlanderGuy F Webster
Jul 24, 2010·Fertility and Sterility·Ethel CodnerFernando Cassorla
Dec 22, 2010·Obstetrics and Gynecology·Erica T WangKirsten Bibbins-Domingo
Jan 5, 2011·Comprehensive Psychiatry·Andre Barciela VerasAntonio E Nardi
Jan 21, 2011·Fertility and Sterility·Robert A WildEnrico Carmina
Feb 22, 2011·Human Reproduction Update·P C M de GrootF M Helmerhorst
Jul 15, 2011·American Journal of Obstetrics and Gynecology·Lucinda E KjerulffDaniel Duffy
Oct 1, 2011·The Journal of Clinical Endocrinology and Metabolism·Johanna SchmidtEva Dahlgren
Oct 4, 2011·Fertility and Sterility·Zoe A BrownJoop S E Laven
Dec 24, 2011·Fertility and Sterility·Kathleen M Hoeger, Sharon E Oberfield
Dec 25, 2012·Molecular and Cellular Endocrinology·Gordon W Bates, Richard S Legro
Feb 15, 2013·International Journal of Impotence Research·C M ErcanI Baser
Jun 27, 2013·Reproductive Biology and Endocrinology : RB&E·Jun Z QinHong Y Chen
Feb 13, 2014·The Journal of Clinical Endocrinology and Metabolism·Alex J PolotskyRichard S Legro
Dec 30, 2014·American Journal of Hypertension·Anju E JohamHelena J Teede
Apr 3, 2015·Hormone Research in Pædiatrics·Selma F WitchelPeter A Lee
Dec 8, 2015·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Neil F GoodmanUNKNOWN Androgen Excess and PCOS Society
Dec 15, 2015·The Journal of Clinical Endocrinology and Metabolism·Meri-Maija E OllilaLaure Morin-Papunen
Aug 12, 2016·Nature Reviews. Disease Primers·Ricardo AzzizBulent O Yildiz
Sep 21, 2017·Clinical Endocrinology·Samira Behboudi-GandevaniFahimeh Ramezani Tehrani
Sep 25, 2017·The Journal of Clinical Endocrinology and Metabolism·Katrine Hass RubinMarianne Andersen

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Citations

May 12, 2021·Clinics in Dermatology·Georgia Kyriakou, Aikaterini Kyriakou
May 28, 2021·Current Obesity Reports·Jaime M MooreMelanie Cree-Green
Jul 23, 2021·International Journal of Adolescent Medicine and Health·Mehrukh ZehraviIrfat Ara
Sep 24, 2021·Frontiers in Endocrinology·Haiyan YangLiangshan Mu

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Methods Mentioned

BETA
cesarean section

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