Characteristics of prostate cancer in men less than 50-year-old

Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
M PeyromaureCCAFU

Abstract

To report the characteristics of prostate cancer (PCa) in men less than 50-year-old and the results of different treatments of PCa in this population. A bibliographic research was performed using Pubmed database. The keywords that we used were: prostate cancer, age, young, radical prostatectomy, brachytherapy, radiotherapy, active surveillance. The studies which included a significant number of patients were selected. A total of 38 articles were used as bibliographic references. PCa in young men does not seem to have different characteristics than in older men. Nevertheless, young men seem to have a lower risk of severe urinary and sexual sequelae, particularly following radical prostatectomy. There is no recommendation regarding management of PCa in men less than 50-year-old. In case of localized cancer, two options may be considered. First option consists in decreasing the urinary and sexual complications of radical prostatectomy. A minimally-invasive treatment, such as brachytherapy or even active surveillance, may reach this objective. Second option consists in being more aggressive. To propose a radical prostatectomy offers to the patient the possibility of salvage radiation therapy in case of locally-advanced tumor or loc...Continue Reading

References

Jul 5, 2005·Urology·Christian TwissHerbert Lepor
Nov 26, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Tan Dat NguyenNicolas Jovenin
Sep 18, 2007·The Journal of Urology·Ahmed MagheliMark L Gonzalgo
Oct 16, 2007·The Journal of Urology·H Ballentine CarterJonathan I Epstein
Aug 13, 2008·Journal of the National Cancer Institute·Anna Bill-AxelsonUNKNOWN Scandinavian Prostate Cancer Group Study Number 4
Mar 1, 1995·Urologic Oncology·M A RiopelJ I Epstein

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Citations

Aug 28, 2015·International Journal of Molecular Medicine·Zhijun WangXingang Cui
Apr 14, 2016·World Journal of Urology·N J KinnearD Foreman
Feb 13, 2018·Oncology Letters·Qiaoli ChenRunsheng Li
Jan 18, 2017·Diagnostic Pathology·Tao TangShiwu Zhang
Aug 13, 2010·Current Opinion in Supportive and Palliative Care

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