Characteristics of registered clinical trials on traditional Chinese medicine for coronavirus disease 2019 (COVID-19): A scoping review.

European Journal of Integrative Medicine
Hui LuoJian-Ping Liu

Abstract

Traditional Chinese medicine (TCM) has been fully committed to the treatment of coronavirus disease 2019 (COVID-19) in China. An increasing number of clinical trials have been registered to evaluate the effects of TCM for COVID-19. The aim of this study was to review the existing TCM clinical trial registrations and identify potentially promising and available TCM therapies, in order to provide a reference for the global management of COVID-19. All clinical trials on TCM for COVID-19 registered in registry platforms worldwide were searched. The data of registration temporal trend, design, objective, interventions, and relevant information were reviewed and summarized. 161 TCM trials were identified from three registries (January 26 to May 14 2020,). Of these, 94 (58.4%) were randomized controlled trials and 114 trials (70.8%) assessed therapeutic effects; while the remainder focused on prevention, rehabilitation, and the epidemiology of TCM syndromes. Eight trials (5.0%) had completed their recruitment. TCM interventions with potential for further evaluation in terms of prevention were moxibustion, Huoxiang Zhengqi pill and Jinye Baidu granules. For treatment of COVID-19, Qingfei Paidu decoction, Huashi Baidu decoction, Lianhua...Continue Reading

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Citations

Mar 16, 2021·Frontiers in Pharmacology·Jieya WuWing Lam
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kaushik ChakravartyJyotika Varshney
Apr 9, 2021·Frontiers in Pharmacology·Le-Le MaDing-Kun Zhang
Jul 27, 2021·Frontiers in Pharmacology·Ziqi ChenLi Deng
Aug 24, 2021·Cell & Bioscience·Azadeh SafarchiFatemeh Vafaee

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Methods Mentioned

BETA
nucleic acid PCR
PCR
Pharmacotherapy

Clinical Trials Mentioned

NCT04285190
NCT04306497
NCT04275388
NCT04257656
NCT04252664

Software Mentioned

Google Scholar

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