Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis isolated from the nasopharynges of asymptomatic children and molecular analysis of S. pneumoniae and H. influenzae strain replacement in the nasopharynx

Journal of Clinical Microbiology
Agnieszka SulikowskaW Hryniewicz

Abstract

Nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in 226 children in different settings (in a crèche [day care center], in an orphanage, and at home) during two seasons (winter and spring) was studied. The rates of carriage of S. pneumoniae and H. influenzae were markedly higher in the crèche and in the orphanage than in the home setting (e.g., 56.5, 63.3, and 25.9%, respectively, for S. pneumoniae in winter). Approximately 80% of the S. pneumoniae isolates identified in the crèche and in the orphanage belonged to the serotypes represented in the seven-valent pneumococcal vaccine, and 4.4% of the children were colonized by H. influenzae type b. Almost all H. influenzae isolates were fully susceptible to the antimicrobial agents tested, and only five (3.6%) produced beta-lactamase; in contrast, 100% of the M. catarrhalis isolates were beta-lactamase positive. Among S. pneumoniae isolates, 36.2% were nonsusceptible to penicillin (PNSP) and 11.8% were fully resistant to penicillin (PRP). All PNSP isolates were obtained from children at the crèche and at the orphanage but not among children brought up at home, and all PRP isolates showed a multiresistant phenotype. Colonization b...Continue Reading

References

Jan 1, 1987·Reviews of Infectious Diseases·G F Van HareC H Kim
Oct 1, 1994·Journal of Clinical Microbiology·T J FallaE R Moxon
Oct 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C AppelbaumM R Jacobs
Mar 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A J LeachJ D Mathews
Jul 1, 1997·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·K G Kristinsson
Feb 13, 1999·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·A TarasiA Pantosti
Aug 10, 1999·The Pediatric Infectious Disease Journal·F GhaffarG H McCracken
Sep 9, 1999·The Journal of Infectious Diseases·N MbelleK P Klugman
Jun 6, 2000·The Journal of Infectious Diseases·J RaymondP Berche
Sep 16, 2000·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·A SkoczyńskaW Hryniewicz
Jul 27, 2001·The Journal of Infectious Diseases·R K SyrjänenA K Takala
Jan 5, 2002·Journal of Medical Microbiology·P MarchisioUNKNOWN Ascanius Project Collaborative Group
Jan 10, 2002·Clinical Microbiology Reviews·Cees M VerduinAlex van Belkum
Feb 1, 1997·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C. PradierP. Dellamonica
Jan 9, 2003·Journal of Clinical Microbiology·Emma MeatsBrian G Spratt
Jan 31, 2003·The Journal of Antimicrobial Chemotherapy·J A García-Rodríguez, M J Fresnadillo Martínez
Apr 19, 2003·Journal of Clinical Microbiology·Henri DabernatPierre Dellamonica
Apr 23, 2003·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Ewa SadowyWaleria Hryniewicz

❮ Previous
Next ❯

Citations

Aug 10, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M K R SogstadD A Caugant
Mar 19, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S YuY Yang
Apr 15, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M Nowosiad, S Giedrys-Kalemba
Jun 13, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P GrzesiowskiUNKNOWN Polish Pediatric IPD Group
Jun 28, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B MikolucR Motkowski
Dec 20, 2005·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·R MatoH de Lencastre
May 30, 2006·The Pediatric Infectious Disease Journal·Edith L G M TonnaerJo H A J Curfs
Jan 11, 2008·Journal of Clinical Microbiology·Koichi HashidaHideaki Suzuki
Dec 14, 2012·The American Naturalist·Sarah Cobey, Marc Lipsitch
Dec 18, 2015·Forensic Science International : Synergy·Cristina Pérez-MartínezAurelio Luna
Oct 17, 2012·Paediatric Respiratory Reviews·Sam Mehr, Nicholas Wood
Mar 5, 2011·International Journal of Pediatric Otorhinolaryngology·Koichi HashidaHideaki Suzuki
Jun 15, 2011·Microbiology and Immunology·Hironori MasakiHiroshi Watanabe
Oct 30, 2013·Pediatric Pulmonology·Charles R EstherPeter H Gilligan
Oct 13, 2006·Vaccine·Peter JacobyUNKNOWN Kalgoorlie Otitis Media Research Project Team
Apr 11, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·V UsonisJ Kirslienė
Mar 21, 2007·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·H ZemlickováP Urbásková
Mar 24, 2016·MBio·Lance E KellerLarry S McDaniel
Jan 1, 2019·Expert Review of Respiratory Medicine·Paula PeyraniGlenn S Tillotson
Nov 23, 2018·The European Respiratory Journal·Sylvia A D RofaelJohn R Hurst
May 5, 2017·The Pediatric Infectious Disease Journal·María Del Mar Ortiz-RomeroUNKNOWN Collaborators of Study Group of Infectious Diseases in the Child in Cartagena
Apr 18, 2020·The Pediatric Infectious Disease Journal·Nicole L MessinaNigel Curtis
Aug 20, 2021·Nature Communications·Zhong-Jie LiUNKNOWN Chinese Centers for Disease Control and Prevention (CDC) Etiology of Respiratory Infection Surveillance Study Team

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.