PMID: 42453Dec 1, 1979

Characteristics of the lymphoid tissue reaction in compensatory reparative growth of the salivary glands in mice

Biulleten' eksperimental'noĭ biologii i meditsiny
N V Iudina


The capacity of the spleen cells of CBA mice to antibody formation as well as to the "graft-versus-host" (GVH) reaction and the change in the stem cell number determined by the spleen colony method were studied after unilateral removal or burn of the submandibular salivary gland and amputation of lower incisors. It is shown that any of these experimental changes in the salivary gland state causes an increase in the stem cell migration and makes lymphocytes more active in inducing the GVH reaction. The ability of spleen lymphocytes to react on additional antigen stimuli increases after amputation of lower incisors, accompanied by an enlargement of salivary glands, and sharply decreases after the removal or burn of the submandibular salivary gland, not causing hypertrophy of salivary glands.


Aug 1, 1982·Biulleten' eksperimental'noĭ biologii i meditsiny·A A Belopol'skiĭE N Pomerantseva


Apr 26, 1963·Science·N K Jerne, A A Nordin

Related Concepts

Mice, Inbred CBA
Graft-vs-Host Disease
Graft Vs Host Reaction
Antibody-Secreting Cells
Salivary Gland Diseases
Natural Regeneration
Hemolytic Plaque Technique
Submandibular Gland

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