Characteristics, treatment and quality of life of stable coronary artery disease patients with or without angina: Insights from the START study

PloS One
Leonardo De LucaSTART Investigators

Abstract

Data on contemporary management patterns of angina in patients with stable coronary artery disease (CAD) are scarce. We sought to describe the current presentation, management, and quality of life of stable CAD patients with or without angina, using the data from the START (STable Coronary Artery Diseases RegisTry) study. START was a prospective, observational, nationwide study aimed to evaluate the presentation, management, treatment and quality of life of stable CAD presenting to cardiologists during outpatient visits or discharged from cardiology wards. Among the 5070 consecutive stable CAD patients enrolled in 183 participating centers over a 3-month period, 3714 (73.2%) had no angina and 1356 (26.8%) presented with angina. Patients with angina underwent more frequently coronary angiography (92.7% vs 84.9%; p<0.0001) and other diagnostic imaging procedures compared to those without angina. In addition, patients with angina received more frequently different combinations of first line therapies and angina relief drugs compared to patients without angina. The quality of life, assessed with the EQ 5D-5L questionnaire, did not differ between the two groups, with the exception of the 'pain or worry' domain that was higher in pat...Continue Reading

Associated Clinical Trials

References

Mar 28, 2007·The New England Journal of Medicine·William E BodenUNKNOWN COURAGE Trial Research Group
Sep 6, 2008·Journal of the American College of Cardiology·Robert A O'Rourke
Apr 12, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M HerdmanX Badia
Sep 11, 2013·BMJ : British Medical Journal·Daniel A JonesAndrew Wragg
Aug 12, 2014·JAMA Internal Medicine·Philippe Gabriel StegUNKNOWN Prospective Observational Longitudinal Registry of Patients With Stable Coronary Artery Disease (CLARIFY) Investigators
Nov 13, 2015·The New England Journal of Medicine·Steven P SedlisUNKNOWN COURAGE Trial Investigators
Jan 20, 2016·Clinical Cardiology·John ZarifisUNKNOWN Investigators of the Prospective, Noninterventional, Observational Study of the Antianginal Efficacy of Ivabradine During a
Mar 24, 2016·The New England Journal of Medicine·E Magnus Ohman

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Citations

Nov 20, 2019·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Delphine De SmedtDirk De Bacquer
Jan 17, 2019·European Heart Journal. Quality of Care & Clinical Outcomes·Leonardo De LucaUNKNOWN START Investigators
Jun 11, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·David MeierStephane Fournier

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Methods Mentioned

BETA
coronary bypass

Clinical Trials Mentioned

NCT01471522

Software Mentioned

SAS

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