Characterization and expression of a sea star otx ortholog (Protxβ1/2) in the larva of Patiriella regularis

Gene Expression Patterns : GEP
Laura EliaMaria Byrne

Abstract

A transcript of otx from the sea star Patiriella regularis (Protxβ1/2) was characterized and its expression in early bipinnaria larvae was documented by whole mount in situ hybridization (WMISH). The nucleotide sequence exhibited 94% identity with Amotxβ1/2 from the closely related species Patiria miniata. Protxβ1/2 was expressed strongly in the developing archenteron in the future fore and mid-gut regions. This was followed by expression of Protxβ1/2 in the developing enterocoels, mesodermal derivatives. This suggests a role for Protx in endomesoderm development. In coelom development, Protxβ1/2 was first expressed in the left coelom. Subsequently expression was evident in the right coelom, but localization was never as strong as in the left coelom. This asymmetry in Protxβ1/2 expression in the coeloms was evident up to the stage when they started to extend posteriorly. These data indicate that Protxβ1/2 may have a role in coelom development, particularly in the left coelom, a definitive adult structure.

References

Mar 7, 1998·Developmental Biology·T KiyamaH Shimada
Mar 8, 2000·Mechanisms of Development·Y HaradaN Satoh
Jul 13, 2000·Genesis : the Journal of Genetics and Development·E ShoguchiN Satoh
Aug 16, 2001·Molecular Biology and Evolution·A GermotS Mazan
Nov 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Veronica F HinmanEric H Davidson
Sep 16, 2005·Development Genes and Evolution·Maria ByrneBronwyn Relf
Jul 14, 2006·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Véronique Duboc, Thierry Lepage
Aug 15, 2008·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Margaret S SmithRudolf A Raff

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