PMID: 6162916Mar 1, 1981Paper

Characterization and purification from human brain of a hyaluronic acid-binding glycoprotein, hyaluronectin

Journal of Neurochemistry
B Delpech, C Halavent

Abstract

Using affinity chromatography and enzyme-labelled immunological assays combined with affinity adsorption, we have obtained evidence for the binding of a brain glycoprotein to hyaluronic acid, and on this basis named it hyaluronectin. This binding was inhibited by hyaluronic acid and by the products of its hydrolysis by hyaluronidase from bovine testis, but was not inhibited by other glycosaminoglycans or by monosaccharides. Preparative affinity chromatography of brain acid-soluble proteins produced hyaluronectin in a good degree of purity. Contamination by albumin was less than 1% and the yield was as high as 80%.

References

Aug 1, 1978·Archives of Biochemistry and Biophysics·L H RomeE F Neufeld
Jan 1, 1978·Journal of Neurochemistry·E Bock
Jul 15, 1977·International Journal of Cancer. Journal International Du Cancer·E Engvall, E Ruoslahti
Jan 1, 1980·Journal of Neuropathology and Experimental Neurology·N GirardR Laumonier
Dec 1, 1956·Journal of Neurochemistry·L G ABOOD, S K ABUL-HAJ

❮ Previous
Next ❯

Citations

Mar 1, 1992·Cancer Metastasis Reviews·E A Turley
Oct 1, 1986·Journal of Neurocytology·A Bignami, D Dahl
Feb 1, 1996·Journal of Neurocytology·P S Eggli, W Graber
Aug 13, 2008·Histochemistry and Cell Biology·Dieter R Zimmermann, María T Dours-Zimmermann
Aug 12, 1982·Brain Research·A DelpechB Delpech
Jan 1, 1985·The International Journal of Biochemistry·D L KalpaxisC P Tsiganos
Jan 1, 1991·The International Journal of Biochemistry·B DelpechP Bertrand
Nov 23, 1987·Journal of Immunological Methods·B DelpechC Chauzy
Oct 31, 1991·Biochimica Et Biophysica Acta·G PeridesA Bignami
Jan 1, 1989·Brain Research Bulletin·A BignamiD Dahl
Jan 1, 1985·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·G NormandG Gombos
Jan 1, 1985·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·A Bignami, B Delpech
Jan 1, 1986·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·M V Alvarado, H V Castejon
Feb 1, 1997·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·S BasuR G Mahajan
May 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·A Bignami, D Dahl
Nov 1, 1993·The Journal of Cell Biology·S K SamuelA H Greenberg
Sep 20, 2000·The Journal of Experimental Medicine·M E MummertA Takashima
Apr 1, 1993·Neuropathology and Applied Neurobiology·D McCormick
Dec 2, 2011·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Christian HagelReinhard E Friedrich
Jan 1, 1990·Journal of Neurochemistry·M S MarksB P Toole
Jan 1, 1990·Journal of Neurochemistry·S Mandal, R G Mahajan
Jan 1, 1987·Acta Oto-laryngologica. Supplementum·T C Laurent
May 1, 1996·Leukemia & Lymphoma·F Smadja-JoffeJ P Levesque
Jan 1, 1989·Connective Tissue Research·E A TurleyJ A Weston
Jan 1, 1993·Connective Tissue Research·K HoareE A Turley
Jan 1, 1994·Progress in Histochemistry and Cytochemistry·R TammiM Tammi
May 1, 1982·The British Journal of Dermatology·A DelpechP Lauret

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.