Characterization of 23 CC chemokine genes and analysis of their expression in channel catfish (Ictalurus punctatus)

Developmental and Comparative Immunology
Baolong BaoZhanjiang Liu

Abstract

Chemokines are a large family of chemotactic cytokines playing crucial roles in the innate immune response. CC chemokines constitute the largest subfamily of chemokines, with 28 CC chemokines identified from mammalian species. However, the status of CC chemokines in teleosts is yet to be determined. We previously identified 26 catfish CC chemokine cDNAs from catfish. In this study, we isolated and sequenced 23 channel catfish CC chemokine genes amounting to a total of over 56 kb of genomic sequences. Genomic organization of the 23 CC chemokine genes was determined by comparing the generated genomic sequences with the previously identified cDNA sequences. Microsatellites were identified from 16 catfish CC chemokine genes allowing them to be utilized for genome mapping. Structural analysis indicated conservation of genomic organization of CC chemokine genes, which may facilitate the establishment of orthologies. Expression of all known catfish CC chemokine transcripts was assessed in nine important tissues. Of the 26 catfish CC chemokine genes, 14 were universally expressed, six were widely expressed in many tissues, while six were highly tissue-specific.

References

Jan 23, 1999·Immunological Reviews·B DixonP Parham
May 20, 1999·American Journal of Human Genetics·L P ZhaoL Hsu
Mar 29, 2001·Nature Immunology·B Moser, P Loetscher
Oct 17, 2001·Developmental and Comparative Immunology·A E Ellis
Apr 2, 2003·Cytokine·UNKNOWN IUIS/WHO Subcommittee on Chemokine Nomenclature
Mar 27, 2004·Developmental and Comparative Immunology·Puttharat BaoprasertkulZhanjiang Liu
Apr 6, 2004·Developmental and Comparative Immunology·Kerry J Laing, Christopher J Secombes
Jul 6, 2004·Molecular Immunology·Kerry J Laing, Christopher J Secombes
Jul 21, 2004·Briefings in Bioinformatics·Sudhir KumarMasatoshi Nei
Jun 10, 2005·Xenotransplantation·Debbie A PlouffeMiodrag Belosevic
Jun 14, 2005·Fish & Shellfish Immunology·Bergljót Magnadóttir
Jun 14, 2005·Molecular Immunology·Puttharat BaoprasertkulZhanjiang Liu
Jul 12, 2005·Fish & Shellfish Immunology·Qun WangZhanjiang Liu

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Citations

Apr 22, 2009·Fish Physiology and Biochemistry·Li-Chen ChenJyh-Yih Chen
Sep 8, 2012·Fish Physiology and Biochemistry·Juan FengYunxin Wang
Dec 4, 2012·International Journal of Molecular Sciences·Lei GaoWeidong Liu
Nov 17, 2015·Biology·Steve Bird, Carolina Tafalla
Feb 12, 2013·Developmental and Comparative Immunology·Jiaren ZhangZhanjiang Liu
Apr 17, 2012·Developmental and Comparative Immunology·Lv-yun ZhuJian-zhong Shao
Mar 19, 2011·Developmental and Comparative Immunology·Alí Alejo, Carolina Tafalla
May 1, 2010·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Zhanjiang Liu
Nov 6, 2007·Fish & Shellfish Immunology·Puttharat BaoprasertkulZhanjiang Liu
Oct 20, 2006·Molecular Immunology·Santiago Fernandez GonzalezAndrew Cossins
Nov 23, 2006·Fish & Shellfish Immunology·Puttharat BaoprasertkulZhanjiang Liu
Jun 27, 2015·Developmental and Comparative Immunology·Chen JiangZhanjiang Liu
Jan 28, 2015·General and Comparative Endocrinology·Jun ZouChris J Secombes
Nov 16, 2013·Molecular Immunology·Prasanth BhattJesu Arockiaraj
Jan 11, 2011·Fish & Shellfish Immunology·Tomoyuki OdakaOsamu Nakamura

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