Characterization of a JAZ7 activation-tagged Arabidopsis mutant with increased susceptibility to the fungal pathogen Fusarium oxysporum.

Journal of Experimental Botany
Louise F ThatcherKemal Kazan

Abstract

In Arabidopsis, jasmonate (JA)-signaling plays a key role in mediating Fusarium oxysporum disease outcome. However, the roles of JASMONATE ZIM-domain (JAZ) proteins that repress JA-signaling have not been characterized in host resistance or susceptibility to this pathogen. Here, we found most JAZ genes are induced following F. oxysporum challenge, and screening T-DNA insertion lines in Arabidopsis JAZ family members identified a highly disease-susceptible JAZ7 mutant (jaz7-1D). This mutant exhibited constitutive JAZ7 expression and conferred increased JA-sensitivity, suggesting activation of JA-signaling. Unlike jaz7 loss-of-function alleles, jaz7-1D also had enhanced JA-responsive gene expression, altered development and increased susceptibility to the bacterial pathogen PstDC3000 that also disrupts host JA-responses. We also demonstrate that JAZ7 interacts with transcription factors functioning as activators (MYC3, MYC4) or repressors (JAM1) of JA-signaling and contains a functional EAR repressor motif mediating transcriptional repression via the co-repressor TOPLESS (TPL). We propose through direct TPL recruitment, in wild-type plants JAZ7 functions as a repressor within the JA-response network and that in jaz7-1D plants, mi...Continue Reading

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Citations

Jun 1, 2016·Journal of Experimental Botany·Christine Shyu
Feb 18, 2017·Marine Drugs·Alexander J WinklerMarta Berrocal-Lobo
Apr 8, 2017·Journal of Experimental Botany·Ziqiang Zhu, Richard Napier
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Feb 6, 2017·Journal of Experimental Botany·Huang HuangSusheng Song
Jan 28, 2021·Plants·Alexey PigolevTatyana Savchenko
Feb 24, 2021·PloS One·Pingdong SunYuanxin Yan
Apr 3, 2021·Horticulture Research·Yunxiao GuanFadi Chen
Apr 7, 2021·Plant Cell Reports·Mouna GhorbelMarco Landi
Apr 12, 2021·BMC Genomics·Yang Han, Dawn Luthe
Sep 26, 2021·The Plant Journal : for Cell and Molecular Biology·Logan DeMottMaeli Melotto
Oct 3, 2021·Journal of Experimental Botany·Lirong ZhaoDiqiu Yu

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