Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid

FEBS Letters
J C Pascall, K D Brown

Abstract

The Drosophila regulatory protein Rhomboid has been demonstrated genetically to facilitate signalling within the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. Using a polymerase chain reaction (PCR)-based strategy, we have cloned a human cDNA which encodes a protein that has high sequence similarity to Rhomboid. The encoded protein, termed rhomboid-related protein (RRP), is predicted to contain seven transmembrane domains. Northern analysis indicates that RRP mRNA is expressed at highest levels in brain and kidney.

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Citations

Nov 26, 1999·Developmental Genetics·B R Lanoue, J R Jacobs
Mar 30, 2004·Biochemical and Biophysical Research Communications·John C Pascall, Kenneth D Brown
Aug 30, 2002·Current Opinion in Genetics & Development·Sinisa Urban, Matthew Freeman
Apr 1, 2008·Animal : an International Journal of Animal Bioscience·S OllierC Leroux
Dec 18, 2002·The EMBO Journal·Matthew Freeman
Nov 5, 2013·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·R CanzoneriM C Abba
Feb 13, 2016·Biomolecules & Therapeutics·Min-Young LeeKyung-Chul Choi
Apr 9, 2013·Biochimica Et Biophysica Acta·Nina Bergbold, Marius K Lemberg
Aug 28, 2012·Biochimica Et Biophysica Acta·Padmapriya SampathkumarM Joanne Lemieux
Oct 26, 2000·Current Biology : CB·M Gallio, P Kylsten
Jan 11, 2007·Proceedings of the National Academy of Sciences of the United States of America·M Joanne LemieuxMichael N G James
Aug 9, 2016·Seminars in Cell & Developmental Biology·Viorica L LastunMatthew Freeman
Oct 23, 2016·Seminars in Cell & Developmental Biology·Kvido Strisovsky
Mar 3, 2004·Nature Reviews. Molecular Cell Biology·Matthew Freeman
Dec 11, 2017·Biomolecules & Therapeutics·Min-Young LeeKi-Hoan Nam
May 30, 2003·Nature·G Angus McQuibbanMatthew Freeman
Aug 14, 2018·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Sandra PaschkowskyLisa Marie Munter
Jun 21, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Takatoshi NakagawaRik Derynck
May 4, 2017·Biochimica Et Biophysica Acta. Molecular Cell Research·Stefan DüsterhöftMatthew Freeman

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