PMID: 3214272Jan 1, 1988Paper

Characterization of a new serotype of infectious pancreatic necrosis virus isolated from Atlantic salmon

Archives of Virology
K E ChristieC Endresen

Abstract

Virus particles isolated from hatchery reared fish with infectious pancreatic necrosis (IPN) were neutralized by homologous immune sera but not by immune sera raised against IPN virus serotype 1, 2, and 3. This virus isolate, called the N1 strain, was detected in one year old Atlantic salmon (Salmo salar) during an outbreak with histopathological lesions of IPN and slightly increased mortality. The polypeptide pattern of N1 virus differed markedly from that of the three classical IPN virus serotypes. Double stranded RNA isolated from the N1 virus particles, co-migrated during agarose gel electrophoresis with nucleic acid isolated from the IPN virus Jasper and Ab strains. Nucleic acid hybridizations using low stringency washing conditions and a synthetic DNA oligonucleotide probe (representing the 3' end of the A segment of the Jasper strain) gave positive results with the IPN virus Jasper, Ab, Sp, and N1 strains. The results presented in this paper show that the N1 isolate differs immunologically and biochemically from the IPN virus serotypes 1, 2, and 3 and may represent a new serotype of IPNV.

References

Feb 1, 1977·The Journal of General Virology·R D Macdonald, T Yamamoto
Apr 1, 1977·Journal of Virology·P DobosD Rowe
Dec 1, 1984·Nihon juigaku zasshi. The Japanese journal of veterinary science·M HattoriH Izawa
Apr 1, 1983·Canadian Journal of Microbiology·P Dobos, T E Roberts
Jan 1, 1984·Intervirology·T O Diener
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Jun 1, 1983·The Journal of General Virology·R P HedrickJ L Fryer
May 1, 1960·Proceedings of the Society for Experimental Biology and Medicine·K WOLFE PYLE

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Citations

Dec 16, 2011·Journal of Virology·Ricardo VanciniDennis Brown
Dec 14, 2011·Viruses·Mark Crane, Alex Hyatt
Aug 9, 2005·Journal of Fish Diseases·R J Roberts, M D Pearson
Nov 24, 2012·The Journal of General Virology·Yong HuangYigang Tong
Nov 22, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tina SvingerudBørre Robertsen
Aug 1, 1995·Applied and Environmental Microbiology·B NovoaA Figueras
Jul 1, 1996·Applied and Environmental Microbiology·M K LeeB L Nicholson

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