Characterization of a Thiol-Ene/Acrylate-Based Polymer for Neuroprosthetic Implants

ACS Omega
Dang-Huy DoWalter E Voit

Abstract

Thiol-ene/acrylate shape-memory polymers can be used as base substrates for neural electrodes to treat neurological dysfunction. Neural electrodes are implanted into the body to alter or record impulse conduction. This study characterizes thiol-ene/acrylate polymers to determine which synthesis methods constitute an ideal substrate for neural implants. To achieve a desired Tg between 50 and 56.5 °C, curing conditions, polymer thickness, monomer ratios, and water uptake were all examined and controlled for. Characterization with dynamic mechanical analysis and thermal gravimetric analysis reveals that thin, thiol-ene/acrylate polymers composed of at least 50 mol % acrylate content and cured for at least 1 h at 365 nm are promising as substrates for neural electrodes.

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Citations

Jul 22, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Matthew R ArkenbergChien-Chi Lin
Feb 7, 2018·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Thitaphat NgernsutivorakulRobert T Kennedy
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Feb 13, 2020·ACS Applied Materials & Interfaces·Drago StickerJörg P Kutter
Nov 10, 2021·Advanced Materials·Gaurav BalakrishnanChristopher J Bettinger

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