PMID: 1541336Jan 1, 1992

Characterization of acetylcholinesterase and butyrylcholinesterase activities in retinal chick pigment epithelium during development

Experimental Eye Research
R Salceda, M T Martinez


The presence of acetylcholinesterase and butyrylcholinesterase was studied in chick retinal pigment epithelium. Acetylcholinesterase activity was 13 times higher than that of butyrylcholinesterase. The former showed a Km of 290 microM and a vmax of 45.4 nmol mg-1 protein min-1, while the latter showed two apparent Km values (132 microM and 666 microM). Studies on subcellular distribution revealed that both enzymes are associated with membranes. During the embryonic development butyrylcholinesterase activity decreased, while acetylcholinesterase activity increased. The possibility that these changes are related to the proliferation and differentiation processes is discussed.


Aug 1, 1995·Journal of Neuroscience Research·G Sánchez-ChávezR Salceda
Dec 8, 2009·Journal of Child Language·Barbara Dodd, Beth McIntosh
Mar 30, 2006·Journal of Experimental Psychology. Learning, Memory, and Cognition·Jörg D JescheniakValentin Wagner


Apr 1, 1976·Canadian Journal of Biochemistry·G TunnicliffA Barbeau
Jun 3, 1975·Biochemistry·D E Moore, G P Hess
Jul 1, 1987·Experimental Eye Research·J B Hutchins
Jan 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·P G Layer, O Sporns
Sep 1, 1974·The Journal of Experimental Zoology·J G Hollyfield, P Witkovsky
Jan 1, 1982·Annual Review of Neuroscience·J Massoulié, S Bon
Oct 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·P G Layer
Sep 1, 1964·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G R DE ARNAIZ

Related Concepts

Pigment Epithelium
Tissue Membrane
Enzymes, antithrombotic
Pigment Epithelium of Eye
Embryonic Development

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.