Characterization of adhesin variants in Indian isolates of enteroaggregative Escherichia coli

FEMS Microbiology Letters
Renu BhardwajAnuradha Chakraborti

Abstract

Enteroaggregative Escherichia coli (EAEC) are causative agents of diarrhea, being characterized by aggregative adherence to cultured epithelial cells. In this study, phenotypic properties of EAEC were analyzed with respect to AA, hemagglutination, clump and biofilm formation, all of which are mediated by aggregative adherence fimbriae (AAF). The strains were also screened for AAF types, AAF adhesin variants and Dr adhesin by PCR. Of the three known AAF types, AAF/I and AAF/II adhesin variants were identified. An association between the AAF/adhesin genotypes and the subtypes/scores of phenotypic properties was sought and it was observed that strains harboring same adhesins displayed different subtypes/scores and vice versa.

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Citations

Apr 30, 2008·Infection and Immunity·Nadia BoisenJames P Nataro
Jun 2, 2009·Journal of Bacteriology·Samhita BhargavaIruka N Okeke
Jun 25, 2016·Microbial Pathogenesis·Deepika GuptaAnuradha Chakraborti
Nov 27, 2019·Journal of Medical Microbiology·Caroline Gastaldi GuerrieriLiliana Cruz Spano

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