Characterization of Candida parapsilosis complex isolates

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
M de ToroJ Aznar

Abstract

Candida parapsilosis former groups II and III have recently been established as independent species, named Candida orthopsilosis and Candida metapsilosis, respectively. We investigated the distribution of C. parapsilosis complex species in 122 isolates from blood and other sources in a southern Spain tertiary-care hospital, and we examined the relationship between species, site of isolation and biofilm positivity. We also evaluated the planktonic MICs and sessile MICs (SMICs) of voriconazole, amphotericin B and anidulafungin. One hundred and eleven isolates (91%) were categorized as C. parapsilosis sensu stricto, whereas ten isolates (8.2%) were categorized as C. orthopsilosis and one (0.8%) as C. metapsilosis. Biofilm positivity was observed in 58.5% (65 of 111) of C. parapsilosis sensu stricto isolates vs. 0% (0 of 11) of C. orthopsilosis and C. metapsilosis isolates (p <0.01). There was no difference in biofilm production among C. parapsilosis sensu stricto isolates from blood and other sources. MIC values showed that all isolates were susceptible to voriconazole and amphotericin B, whereas two isolates (1.8%) of C. parapsilosis sensu stricto were non-susceptible to anidulafungin. However, the MIC₉₀ value of voriconazole was...Continue Reading

References

Sep 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·C GirmeniaA Cassone
Feb 7, 2001·Clinical Microbiology Reviews·D R Soll
Feb 7, 2001·Journal of Clinical Microbiology·L EngerD R Soll
Aug 15, 2001·Antimicrobial Agents and Chemotherapy·G RamageJ L López-Ribot
Oct 2, 2002·Journal of Clinical Microbiology·M A Pfaller, D J Diekema
Jun 23, 2004·Emerging Infectious Diseases·Duncan M KuhnMahmoud A Ghannoum
Jan 16, 2007·Clinical Microbiology Reviews·M A Pfaller, D J Diekema
Oct 17, 2007·Antimicrobial Agents and Chemotherapy·Aspasia KatragkouEmmanuel Roilides
Jun 17, 2008·Diagnostic Microbiology and Infectious Disease·Eveline van AsbeckDavid A Stevens
Oct 16, 2008·Clinical Microbiology Reviews·David TrofaJoshua D Nosanchuk

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Citations

May 7, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·I Quiles-MeleroJ Mingorance
Jun 21, 2013·Journal of Clinical Microbiology·Tâmara Heloísa Rocha PrandiniEduardo Bagagli
May 9, 2012·PloS One·Alessandro RiccombeniGeraldine Butler
Dec 25, 2015·Journal de mycologie médicale·M AsadzadehZ Khan
Apr 26, 2014·Scandinavian Journal of Infectious Diseases·Mar Martí-CarrizosaPere Coll
Aug 6, 2016·Diagnostic Microbiology and Infectious Disease·Sandra Gil-AlonsoGuillermo Quindós
Feb 19, 2017·Revista iberoamericana de micología·Débora de Souza Olartechea de AlencarMarilene Rodrigues Chang
May 10, 2017·Antimicrobial Agents and Chemotherapy·Maria Emilia CattanaGustavo Giusiano
Mar 23, 2011·Expert Review of Anti-infective Therapy·Anıl Tapısız
May 31, 2018·Journal of Medical Microbiology·Raimunda Sâmia Nogueira BrilhanteMarcos Fábio Gadelha Rocha
Oct 13, 2018·The Science of the Total Environment·Raimunda Sâmia Nogueira BrilhanteMarcos Fábio Gadelha Rocha

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