Characterization of chronic urticaria and associated conditions in a large population of adolescents

Journal of the American Academy of Dermatology
Yossi RosmanRonit Confino-Cohen

Abstract

Although chronic spontaneous urticaria (CSU) affects all age groups, data regarding CSU in adolescents is scarce. To characterize the epidemiology, demographics, and comorbidities associated with CSU in a large, cross-sectional nationwide population of adolescents. Medical records of 16-year-old candidate conscripts to the Israeli Defense Forces were reviewed. Data were collected on the prevalence and severity of CSU, as well as the demographics, medical comorbidities, medication use, and blood test results of affected individuals. Medical records of 1,108,833 consecutive 16-year-old adolescents were reviewed. A total of 6617 (0.6%) adolescents received CSU diagnoses. CSU was increased in female conscripts (odds ratio [OR] 1.13, 95% confidence interval [CI] 1.07-1.19, P < .001) and adolescents with higher socioeconomic scores (OR 1.92, 95% CI 1.56-2.32, P < .001). Individuals with CSU were significantly more likely to have allergic diseases, including food allergy (OR 7.31, 95% CI 6.13-8.72), allergic rhinitis (OR 2.9, 95% CI 2.71-3.11), atopic dermatitis (OR 2.35, 95% CI 2.03-2.72), and asthma (OR 1.46, CI 1.35-1.57). Our work provides an account of CSU in a large cohort of adolescents. We found a strong link between CSU and a...Continue Reading

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Citations

Jul 10, 2020·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Yu-Mi ParkJi-Won Kwon
Sep 19, 2019·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Ciara Jade Bansal, Amolak Singh Bansal
Feb 21, 2021·BMC Pediatrics·Leelawadee TechasatianRattapon Uppala
Jan 28, 2021·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Idit Lachover-RothRonit Confino-Cohen
Sep 17, 2021·Clinical Reviews in Allergy & Immunology·Liting HeQianjin Lu
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Feb 6, 2020·Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry·Anna TagkaAlexandra Katsarou

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