Characterization of coaggregation between Bacteroides gingivalis T22 and Fusobacterium nucleatum T18.

Infection and Immunity
S A Kinder, S C Holt

Abstract

Bacterial adherence is a key factor in the colonization of the oral ecosystem, yet little is known about the mechanisms by which the pathogen Bacteroides gingivalis adheres in the periodontal environment. We examined the ability of strains of B. gingivalis to coaggregate with selected microorganisms isolated from the subgingival microbiota of the cynomolgus monkey. A strong interaction was demonstrated between strains of B. gingivalis and Fusobacterium nucleatum, whereas less pronounced or no interaction was observed with other oral isolates. Electron microscopic examination of coaggregates revealed large masses of bacteria, in which the fusiform F. nucleatum T18 and coccobacillary B. gingivalis T22 cells formed a woven pattern. To investigate this interaction and the nature of the bacterial cell surface molecules involved, we used a microcoaggregation assay. Galactose and galactose-related sugars blocked coaggregation, in contrast with the lack of effect of glucose or glucose-related sugars. The ability of F. nucleatum T18 cells to coaggregate was diminished by pretreatment with pronase. Pretreatment of B. gingivalis T22 cells with pronase resulted in an inhibition of coaggregation, whereas pretreatment with sodium metaperioda...Continue Reading

References

Jan 1, 1979·Archives of Oral Biology·J R Mongiello, W A Falkler
Mar 1, 1977·Journal of Periodontal Research·S S SocranskyJ van Houte
Jan 1, 1977·Infection and Immunity·W A Falkler, C E Hawley
Sep 1, 1978·Infection and Immunity·S A Syed, W J Loesche
Sep 1, 1978·Infection and Immunity·W J Loesche, S A Syed
May 1, 1988·Infection and Immunity·P A MurrayJ R Winkler
Jun 27, 1985·The New England Journal of Medicine·B E BritiganP F Sparling
Feb 1, 1989·Infection and Immunity·J Kaufman, J M DiRienzo
Jan 1, 1989·Journal of Medical Microbiology·P I EkeB E Laughon
Jan 1, 1988·Annual Review of Microbiology·P E Kolenbrander
Mar 1, 1988·Microbiological Reviews·D Mayrand, S C Holt
Jul 1, 1987·Analytical Biochemistry·A PrakobpholS J Fisher
Sep 1, 1987·Reviews of Infectious Diseases·E H Beachey, H S Courtney
Jun 1, 1986·Journal of Clinical Microbiology·S A KinderK S Korman
Nov 1, 1986·Journal of Bacteriology·P E Kolenbrander, R N Andersen
Aug 1, 1985·Journal of Clinical Microbiology·S S SocranskyC M Smith
Nov 22, 1965·Biochemical and Biophysical Research Communications·L Leive
Jun 1, 1973·Journal of Periodontology·R J Gibbons, J van Houte
Dec 1, 1970·Archives of Oral Biology·R J Gibbons, M Nygaard
Apr 1, 1983·Infection and Immunity·P LancyS C Holt
Mar 1, 1980·Journal of Periodontal Research·S A SyedG Svanberg
Jul 1, 1981·Journal of Periodontal Research·K S KornmanP B Robertson
Nov 1, 1980·Journal of Periodontal Research·J L EbersoleD J Smith
May 1, 1965·Journal of Periodontology·H LOES B JENSEN

❮ Previous
Next ❯

Citations

May 1, 1991·Journal of Periodontal Research·S S Socransky, A D Haffajee
Jan 1, 1991·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·S C Holt, T E Bramanti
Sep 1, 1995·Oral Diseases·J L EbersoleS C Holt
Jun 27, 1998·Periodontology 2000·W G Wade, M A Slayne
Jan 12, 2001·Oral Microbiology and Immunology·R J Lamont, H F Jenkinson
Nov 6, 2001·Microbiology and Immunology·A KamaguchH Baba
Jan 5, 2008·Oral Microbiology and Immunology·M Al-HaroniP Cash
May 24, 2008·International Journal of Cosmetic Science·Y Lu, G V Levin
Jun 14, 2012·International Journal of Dentistry·Masahiro YonedaTakao Hirofuji
Jun 1, 1992·FEMS Microbiology Reviews·H J BusscherH C van der Mei
May 9, 1998·Oral Microbiology and Immunology·B ShaniztkiE I Weiss
Nov 1, 1993·Journal of Periodontal Research·M S LantzS C Holt
Aug 1, 1994·Oral Microbiology and Immunology·P N MadianosJ Sandros
Aug 11, 1992·Oral Microbiology and Immunology·J C BaumgartnerT Beckerman
May 1, 1993·Journal of Periodontal Research·J SandrosG Dahlén
Jan 1, 1997·Journal of Periodontal Research·H KuramitsuM I Cho
Jun 1, 1994·Periodontology 2000·J L Ebersole, M A Taubman
Jan 1, 1993·The Journal of Applied Bacteriology·P E Kolenbrander
Sep 22, 2006·Infection and Immunity·Carlo Amorin DaepDonald R Demuth
Apr 27, 2004·Periodontology 2000·Neil M O'Brien-SimpsonEric C Reynolds
Oct 1, 1992·The Journal of Applied Bacteriology·M AddyW G Wade
Oct 25, 1996·Annals of the New York Academy of Sciences·A SadzieneA G Barbour
Sep 2, 2003·Journal of Bacteriology·Karen E NelsonClaire M Fraser
Oct 1, 1993·Oral Microbiology and Immunology·R J LamontB Rosan
Oct 11, 1992·Oral Microbiology and Immunology·K S George, W A Falkler
Oct 16, 1999·Periodontology 2000·S C HoltC A Genco
Dec 19, 2009·Periodontology 2000·Masae Kuboniwa, Richard J Lamont

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.