Characterization of collagen/hydroxyapatite composite sponges as a potential bone substitute

International Journal of Biological Macromolecules
Alina Sionkowska, Justyna Kozłowska

Abstract

Hydroxyapatite and collagen composites (HAp/Col) have the potential in mimicking and replacing skeletal bones. Their combination should prove beneficial for bone tissue engineering due to their natural biological resemblance and properties. In this study, hydroxyapatite and collagen isolated from animal tendons were used in different proportions as composites. Sponges were prepared by freezing and lyophilization of corresponding composite solutions. The properties of composite sponges, such as microstructure, chemical and physical properties were studied. In the present investigation, a collagen sponge and a composite sponge made of composite of HAp/Col were prepared in our lab and characterized by attenuated total reflection Fourier transform infra-red spectroscopy, thermogravimetric analysis and scanning electron microscopy (SEM). Infrared spectroscopy (IR) in combination with attenuated total reflection (ATR) spectroscopy is one of the most widely used technique for surface infrared analysis. The ATR-IR analysis did not indicate shift of the band corresponding to -COO(-) for none of the used HAp/Col ratios. Thermogravimetric results suggested that collagen chains had been embedded with HAp to several complexes with different...Continue Reading

References

Oct 4, 2002·Biomaterials·Myung Chul Chang, Junzo Tanaka
Oct 20, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hideki Yoshikawa, Akira Myoui
Feb 24, 2006·Colloids and Surfaces. B, Biointerfaces·Nebahat DegirmenbasiElvan Birinci

❮ Previous
Next ❯

Citations

Mar 4, 2014·Materials Science & Engineering. C, Materials for Biological Applications·Gheorghe TomoaiaMaria Tomoaia-Cotisel
Apr 3, 2012·Tissue Engineering. Part B, Reviews·Amanda N Renth, Michael S Detamore
Aug 12, 2015·Journal of Functional Biomaterials·Sergey V Dorozhkin
Sep 26, 2012·Journal of Biomedical Materials Research. Part a·Sandra C RodriguesFernando J Monteiro
Apr 10, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Leszek BorkowskiGrażyna Ginalska
Jun 9, 2012·International Journal of Biological Macromolecules·Zhuojun MengQiaoling Zhao
Jun 5, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Leszek BorkowskiGrażyna Ginalska
Oct 16, 2012·International Journal of Biological Macromolecules·A Sionkowska, J Kozłowska
Dec 30, 2014·International Journal of Biological Macromolecules·J Kozłowska, A Sionkowska
Dec 16, 2016·Journal of Biomedical Materials Research. Part a·Cristian MartínezDaniel G Olmedo
Feb 7, 2018·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Leszek BorkowskiGrazyna Ginalska
Aug 14, 2019·Journal of Biomedical Materials Research. Part a·Mehdi RazaviAvnesh S Thakor
Aug 5, 2017·Materials·Piergiorgio GentileAna Marina Ferreira
Oct 16, 2012·Analytica Chimica Acta·Zarah WalshMirek Macka
Apr 20, 2021·Colloids and Surfaces. B, Biointerfaces·Karuppusamy Shanmugapriya, Hyun Wook Kang
Mar 27, 2012·International Journal of Biological Macromolecules·Venkatachalam NatarajanBalaraman Madhan
Oct 1, 2012·Materials Science & Engineering. C, Materials for Biological Applications·Wen-Bing TienPin-Chuan Yao
Jan 20, 2021·ACS Biomaterials Science & Engineering·Gabriela S DiogoTiago H Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of the Royal Society, Interface
M NavarroJ A Planell
Colloids and Surfaces. B, Biointerfaces
Nebahat DegirmenbasiElvan Birinci
Journal of Materials Science. Materials in Medicine
Shunji YunokiJunzo Tanaka
© 2021 Meta ULC. All rights reserved