Characterization of full genome sequences of chicken anemia viruses circulating in Egypt reveals distinct genetic diversity and evidence of recombination

Virus Research
Ahmed M ErfanMahmoud M Naguib

Abstract

Chicken anemia virus (CAV) is one of the commercially important diseases of poultry worldwide. In Egypt, CAV has been reported to be a potential threat to the commercial poultry sectors. Hence, this study was aimed at isolation and full genomic analysis of CAVs circulating in chicken populations in different geographical location in Egypt. A total of 42 samples were collected from broiler chicken flocks in 9 governorates in Egypt from 12 to 42 days of age. The mortality rate observed among chickens was ranging from 3% to 22%. Nineteen out of 42 farms were found positive for the CAV genome by polymerase chain reaction (PCR). Full genome sequencing was conducted for 18 positive samples. Genetic analysis revealed a high similarity of >99% in 11 viruses with the vaccine strain Del-Ros; while the other seven samples shared close similarity to CAV field strains isolated from China, Taiwan, and Brazil. The data also indicated Q139 and Q144 amino acids substitutions among the VP1 of Egyptian field strains, which are known to be important in virus replication and spread. Phylogenetic analysis of the sequenced viruses (n = 18) based on either the full gene nucleotide sequence or VP1 coding sequence, suggested the circulation of four dist...Continue Reading

References

Aug 1, 1991·The Journal of General Virology·J A ClaessensP J Sondermeijer
Jun 1, 1991·Avian Pathology : Journal of the W.V.P.A·M S McNulty
Oct 1, 2000·Avian Pathology : Journal of the W.V.P.A·D Todd
Mar 20, 2009·The Onderstepoort Journal of Veterinary Research·D O OluwayeluO D Olaleye
Nov 15, 2011·Virology Journal·Yassir M EltahirAijian Qin
Sep 11, 2012·Virology Journal·Chantal J SnoeckClaude P Muller
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley
Oct 11, 2014·Advances in Virology·Mohammed AboElkhairAbd Elnaby Y Metwally
Nov 6, 2014·Molecular Biology and Evolution·Lam-Tung NguyenBui Quang Minh
Mar 10, 2016·Avian Diseases·Monika Olszewska-TomczykKrzysztof Śmietanka
May 26, 2015·Virus Evolution·Darren P MartinBrejnev Muhire

❮ Previous
Next ❯

Citations

Nov 2, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·S M SreekalaP N Dwivedi
Apr 4, 2021·Animals : an Open Access Journal From MDPI·Giulia QuagliaCaterina Lupini
May 1, 2021·Avian Pathology : Journal of the W.V.P.A·Claudia TecheraRuben Pérez

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.