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Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

BMC Nephrology

Nov 14, 2019

Flavia Teodora Ioana PaunasBjørn Egil Vikse

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Abstract

IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. In the present study we used mass spectrometry-based proteomics in order to quantitativel...read more

Mentioned in this Paper

Biological Markers
Biopsy
Extracellular Matrix
IGA Glomerulonephritis
Immunoglobulin A
Inflammation
Kidney Failure, Chronic
Peroxidase
Neutrophil
Viral Structural Proteins
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Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli

BMC Nephrology

Nov 14, 2019

Flavia Teodora Ioana PaunasBjørn Egil Vikse

PMID: 31726998

DOI: 10.1186/s12882-019-1598-1

Abstract

IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. In the present study we used mass spectrometry-based proteomics in order to quantitativel...read more

Mentioned in this Paper

Biological Markers
Biopsy
Extracellular Matrix
IGA Glomerulonephritis
Immunoglobulin A

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